Perceptual learning (PL) involves long-lasting improvement in perceptual tasks following extensive training and is accompanied by modified neuronal responses in sensory cortical areas in the brain. Understanding the dynamics of PL and the resultant synaptic changes is important for causally connecting PL to the observed neural plasticity. This is theoretically challenging because learning-related changes are distributed across many stages of the sensory hierarchy.
View Article and Find Full Text PDFElucidation of the chemical structure and formation mechanism of humins is a requisite to further improve the efficiency of acid-catalyzed biomass conversion. Through a low-temperature approach, the key intermediates resulting in the formation of 5-hydroxymethylfurfural (HMF)-derived humins were captured, revealing multiple elementary reactions such as etherification, esterification, aldol condensation, and acetalization. Through humin characterization, it was found out that the aldol condensation moiety between aldehyde group and levulinic acid is critical to justify the characteristic IR peaks (1620 and 1710 cm ) and aromatic fragments from pyrolysis GC-MS.
View Article and Find Full Text PDFDiffusion processes with boundaries are models of transport phenomena with wide applicability across many fields. These processes are described by their probability density functions (PDFs), which often obey Fokker-Planck equations (FPEs). While obtaining analytical solutions is often possible in the absence of boundaries, obtaining closed-form solutions to the FPE is more challenging once absorbing boundaries are present.
View Article and Find Full Text PDFProc Biol Sci
November 2017
Well over 90% of studies in biomedical sciences are performed on single animals. While knowledge of the genetics, development and physiology of single individuals accrues, an understanding of the biological mechanisms by which individuals interact has barely budged. Yet many of society's greatest problems derive from an inability of humans to get along with each other.
View Article and Find Full Text PDFDespite decades of research with humans, the biological mechanisms that motivate an individual to help others remain poorly understood. In order to investigate the roots of pro-sociality in mammals, we established the helping behavior test, a paradigm in which rats are faced with a conspecific trapped in a restrainer that can only be opened from the outside. Over the course of repeated test sessions, rats exposed to a trapped cagemate learn to open the door to the restrainer, thereby helping the trapped rat to escape (Ben-Ami Bartal et al.
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