Recombinant Humanized Collagen Enhances Secreted Protein Levels of Fibroblasts and Facilitates Rats' Skin Basement Membrane Reinforcement.

Collagen and its peptides exhibit remarkable antioxidant activity, superior biocompatibility, and water solubility, making them a significant research focus in skin care. Hence, the recombinant humanized collagen types I, III, and XVII complexed with niacinamide were developed to address damage in human foreskin fibroblasts (HFF-1) caused by ultraviolet radiation and to evaluate basement membrane proteins in a rat skin model. The Cell Counting Kit-8 (CCK-8) assay showed that higher concentrations of the complex increased the survival of damaged cells by approximately 10% and 22%, respectively, compared to the normal group after 16 and 48 h of treatment.

Study on the effect factors of discharge readiness of total hip arthroplasty patients.

Introduction: In order to explore the correlation between discharge readiness and Harris score or self-care ability of patients undergoing total hip arthroplasty (THA) based on the enhanced recovery after surgery (ERAS) concept. We carried out this single center retrospective study.

Methods: We enrolled 331 patients who underwent THA.

Bone-targeted ICG/Cyt c@ZZF-8 nanoparticles based on the zeolitic imidazolate framework-8: a new synergistic photodynamic and protein therapy for bone metastasis.

Bone metastasis (BM) is a solid tumor confined to narrow bone marrow cavities with a relatively poor blood supply and hypoxic environment, making conventional anticancer treatments difficult. In our study, we fabricated nanoparticles (NPs) based on zeolitic imidazolate framework-8 (ZIF-8) loaded with indocyanine green (ICG, a photodynamic agent) and cytochrome c (Cyt c, an anticancer protein) with a surface modified by zoledronate (ZOL, a bone-targeting moiety) and a polyvinyl pyrrolidone (PVP) coating to increase their stability. The ICG/Cyt c@ZZF-8 NPs were expected to have synergistic antitumor therapy and bone protection efficiency.

Luminescence and Stability Enhancement of Inorganic Perovskite Nanocrystals via Selective Surface Ligand Binding.

Colloidal lead halide perovskite nanocrystals (NCs) have recently emerged as one of the most promising light-emitting materials for optoelectronic devices with outstanding performance. However, the facile detachment of surface capping organic ligands from these NCs leads to very poor colloidal stability and durability. This is mainly due to the weak interfacial interactions between the inorganic perovskite core and ligands, high density of surface defect states, and aggregation of NCs.

Cyanamide Passivation Enables Robust Elemental Imaging of Metal Halide Perovskites at Atomic Resolution.

Lead halide perovskites (LHPs) have attracted a tremendous amount of attention because of their applications in solar cells, lighting, and optoelectronics. However, the atomistic principles underlying their decomposition processes remain in large part obscure, likely due to the lack of precise information about their local structures and composition along regions with dimensions on the angstrom scale, such as crystal interfaces. Aberration-corrected scanning transmission electron microscopy combined with X-ray energy dispersive spectroscopy (EDS) is an ideal tool, in principle, for probing such information.

Correlation of Photoluminescence and Structural Morphologies at the Individual Nanoparticle Level.

Single-particle spectroscopy has demonstrated great potential for analyzing the microscopic behavior of various nanoparticles (NPs). However, high-resolution optical imaging of these materials at the nanoscale is still very challenging. Here, we present an experimental setup that combines high sensitivity of time-correlated single-photon counting (TCSPC) techniques with atomic force microscopy (AFM).

Delayed Photoluminescence and Modified Blinking Statistics in Alumina-Encapsulated Zero-Dimensional Inorganic Perovskite Nanocrystals.

We demonstrate enhancement of the photoluminescence (PL) properties of individual zero-dimensional (0D) CsPbBr perovskite nanocrystals (PNCs) upon encapsulation by alumina using an appropriately modified atomic layer deposition method. In addition to the increased PL intensity and improved long-term stability of encapsulated PNCs, our single-particle studies reveal substantial changes in the PL blinking statistics and the persistent appearance of the long-lived, "delayed" PL components. The blinking patterns exhibit a modification from the fast switching between fluorescent ON and OFF states found in bare PNCs to a behavior with longer ON states and more isolated OFF states in alumina-encapsulated PNCs.

Emergence of multiple fluorophores in individual cesium lead bromide nanocrystals.

Cesium-based perovskite nanocrystals (PNCs) possess alluring optical and electronic properties via compositional and structural versatility, tunable bandgap, high photoluminescence quantum yield and facile chemical synthesis. Despite the recent progress, origins of the photoluminescence emission in various types of PNCs remains unclear. Here, we study the photon emission from individual three-dimensional and zero-dimensional cesium lead bromide PNCs.

Point Defects and Green Emission in Zero-Dimensional Perovskites.

Zero-dimensional (0D) perovskites have recently opened a new frontier in device engineering for light conversion technologies due to their unprecedented high photoluminescence quantum yield as solids. Although many experimental and theoretical efforts have been made to understand their optical behavior, the origin of their green emission is still opaque. Here, we develop a complete experimental and theoretical picture of point defects in Cs-Pb-Br perovskites and demonstrate that bromide vacancies (V) in prototype 0D perovskite CsPbBr have a low formation energy and a relevant defect level to contribute to the midgap radiative state.

Zero-Dimensional CsPbBr Perovskite Nanocrystals.

Perovskite nanocrystals (NCs) have become leading candidates for solution-processed optoelectronics applications. While substantial work has been published on 3-D perovskite phases, the NC form of the zero-dimensional (0-D) phase of this promising class of materials remains elusive. Here we report the synthesis of a new class of colloidal semiconductor NCs based on CsPbBr, the 0-D perovskite, enabled through the design of a novel low-temperature reverse microemulsion method with 85% reaction yield.

Mapping Carrier Dynamics on Material Surfaces in Space and Time using Scanning Ultrafast Electron Microscopy.

Selectively capturing the ultrafast dynamics of charge carriers on materials surfaces and at interfaces is crucial to the design of solar cells and optoelectronic devices. Despite extensive research efforts over the past few decades, information and understanding about surface-dynamical processes, including carrier trapping and recombination remains extremely limited. A key challenge is to selectively map such dynamic processes, a capability that is hitherto impractical by time-resolved laser techniques, which are limited by the laser's relatively large penetration depth and consequently these techniques record mainly bulk information.