The optimal intravesical maintenance chemotherapy scheme for the intermediate-risk group non-muscle-invasive bladder cancer.

Objective: Although the current European Association of Urology(EAU) guideline recommends that patients with intermediate-risk non-muscle-invasive bladder cancer (NMIBC) should accept intravesical chemotherapy or Calmette-Guerin (BCG) for no more than one year after transurethral resection of bladder tumor(TURBT), there is no consensus on the optimal duration of chemotherapy. Hence, we explored the optimal duration of maintenance intravesical chemotherapy in patients with intermediate-risk NMIBC.

Subjects And Methods: This was a real-world single-center retrospective cohort study.

Venous thrombosis, multiple carcinomatous foci and differences in metastatic pathways of penile carcinoma.

The aim of the present study was to explore the life-threatening complications and metastatic pathways of penile squamous cell carcinoma (SCC), as numerous patients with penile cancer are relatively young, are of good general health and have no visceral metastasis, yet have poor survival rates. A total of 94 patients with SCC of the penis who were surgically treated were included in the current study. The coagulation parameters, including prothrombin time (PT), fibrinogen and D-dimer, were analyzed.

The efficacy of 3D personalized insoles in moderate adolescent idiopathic scoliosis: a randomized controlled trial.

Background: Bracing and exercise methods were used in scoliosis rehabilitation and proven effective. There was little evidence about the efficacy of insoles on scoliosis.

Objective: This study aimed to investigate the effects of 3D personalized insoles on curve magnitude, postural stability, and quality of life (QOL) in moderate adolescent idiopathic scoliosis (AIS) patients.

Inverse centrifugal effect induced by collective motion of vortices in rotating thermal convection.

When a fluid system is subject to strong rotation, centrifugal fluid motion is expected, i.e., denser (lighter) fluid moves outward (inward) from (toward) the axis of rotation.

Urine-based regenerative RNA biomarkers for urinary bladder wound healing.

This study aimed to investigate the expression of regeneration-related genes in canine urine during bladder repair. Canine urine samples were collected after partial cystectomy. Regenerative mRNA of hypoxia-inducible factor (HIF), vascular endothelial growth factor (VEGF), key stem cell transcription factors and cholinergic signals were detected.

Deep-ultraviolet femtosecond laser source at 243 nm for hydrogen spectroscopy.

This paper reports on the generation of a 100 MHz repetition rate, 1.7 mW average power and femtosecond deep-ultraviolet (DUV) 243 nm laser source. The infra-red output of a broadband Titanium-Sapphire (TiSa) laser containing 729 nm light is mixed with its second harmonic in a β-barium borate (BBO) crystal.

Applying MRI Intensity Normalization on Non-Bone Tissues to Facilitate Pseudo-CT Synthesis from MRI.

This study aimed to facilitate pseudo-CT synthesis from MRI by normalizing MRI intensity of the same tissue type to a similar intensity level. MRI intensity normalization was conducted through dividing MRI by a shading map, which is a smoothed ratio image between MRI and a three-intensity mask. Regarding pseudo-CT synthesis from MRI, a conversion model based on a three-layer convolutional neural network was trained and validated.

Vortices as Brownian particles in turbulent flows.

Brownian motion of particles in fluid is the most common form of collective behavior in physical and biological systems. Here, we demonstrate through both experiment and numerical simulation that the movement of vortices in a rotating turbulent convective flow resembles that of inertial Brownian particles, i.e.

A Deep Ultraviolet Mode-locked Laser Based on a Neural Network.

Deep ultraviolet lasers based on the phenomenon of mode-locking have been used widely in many areas in recent years, for example, in semiconductors, the environment and biomedicine. In the development of a mode-locked deep ultraviolet laser, one of the most important aspects is to optimize the multiple parameters of the complex system. Traditional optimization methods require experimenters with more optimization experience, which limits the wide application of the lasers.

Comparison of Cd adsorption onto amphoteric, amphoteric-cationic and amphoteric-anionic modified magnetic bentonites.

Organic-magnetic bentonites (OMBts), i.e., amphoteric modified MBt (BS-MBt), amphoteric-cationic modified MBt (BS-CT-MBt) and amphoteric-anionic modified MBt (BS-SDS-MBt), obtained by modifying magnetic bentonite (MBt) with amphoteric surfactant (BS), cationic surfactant (CT) and anionic surfactant (SDS) were investigated with the aim to remove cadmium (Cd).

The enhanced expression of estrogen-related receptor α in human bladder cancer tissues and the effects of estrogen-related receptor α knockdown on bladder cancer cells.

Estrogen-related receptor α (ERRα) belongs to the superfamily of nuclear orphan receptors. However, the role of ERRα in bladder cancer remains unknown. This study examined the expression of ERRα in bladder cancer tissues and explored the molecular mechanisms of ERRα in bladder cancer progression.

Muscarinic cholinergic signaling and overactive bladder-like symptoms associated with invasive bladder cancer.

The objective of the present study was to explore the association between muscarinic cholinergic signaling and urothelial bladder tumors. Possible associations among overactive bladder (OAB) symptoms and bladder tumors were retrospectively investigated using a multicenter Chinese database with prospectively collected data since 2010. Firstly, it was demonstrated that OAB symptoms, such as urgency, were more severe in patients with invasive bladder cancer and were associated with a reduced prognosis.

A rare life-threatening disease: unilateral kidney compressed by huge chronic spontaneous retroperitoneal hemorrhage.

Objectives: To study an uncommon life-threatening disease, spontaneous retroperitoneal and perirenal hemorrhage.

Case Descriptions: A 69-year-old male presented with pain in the left waist and back of 1 month duration. The renal abscess was suspected by magnetic resonance imaging before operation.

The properties and dynamic changes of DOM subfractions during food waste and sugarcane leaves co-composting.

The purpose of this research was to evaluate the properties and dynamic changes of humic acids (HA), fulvic acids (FA), hydrophobic neutrals (HoN), and hydrophilic (Hi) fractions of dissolved organic matter (DOM) during food waste and sugarcane leaves co-composting process. The pools of HA, FA, HoN, and Hi were separated from DOM by fractionation method, and characterized using spectroscopic (UV-vis, FTIR) and pyrolysis-GC/MS analyses. The least peaks in the HA pool were found in FTIR spectra with the simple structure in HA.

Chip Scale Atomic Resonator Frequency Stabilization System With Ultra-Low Power Consumption for Optoelectronic Oscillators.

We present a long-term chip scale stabilization scheme for optoelectronic oscillators (OEOs) based on a rubidium coherent population trapping (CPT) atomic resonator. By locking a single mode of an OEO to the (85)Rb 3.035-GHz CPT resonance utilizing an improved phase-locked loop (PLL) with a PID regulator, we achieved a chip scale frequency stabilization system for the OEO.

Cystitis glandularis: A controversial premalignant lesion.

Cystitis glandularis (CG) has been hypothesized as a potential precursor of adenocarcinoma, although this remains controversial. The present study reports data accumulated from 166 cases of cystitis glandularis with follow-up periods ranging between 0.5 and 17 years.