The association of non-vitamin K antagonist oral anticoagulants warfarin and the risk of fractures for patients with atrial fibrillation: a systematic review and meta-analysis.

Background: The fracture risks of non-vitamin K antagonist oral anticoagulants (NOACs) warfarin in patients with atrial fibrillation (AF) remain controversial.

Methods: PubMed, Cochrane Library, EMBASE, Clinical Trials.gov databases for RCTs, and cohort studies were systematically searched from inception to 10 June 2021.

Efficacy and safety of direct oral anticoagulants for the treatment of cancer-associated venous thromboembolism: A systematic review and Bayesian network meta-analysis.

Introduction: Direct oral anticoagulants (DOACs) could effectively prevent the occurrence of cancer-associated venous thromboembolism (CAVTE), which incidence rate was estimated to be 4-20%. But the efficacy and safety remain controversial between DOACs and low molecular weight heparin (LMWH).

Materials And Methods: PubMed, Cochrane Library, Embase, ClinicalTrials.