Publications by authors named "Haoxin Cai"
Article Synopsis
- Injectable hydrogels with fibrous structures are gaining attention for cartilage repair due to their mechanical and biological properties.
- A new chemically cross-linked hydrogel called CSSH-PP was developed to improve cell proliferation and cartilage regeneration, showing a 100% increase in compressive strength over traditional hydrogels.
- In animal studies, CSSH-PP enhanced cell migration and host cell infiltration, promoting blood vessel formation and improving tissue repair in damaged cartilage.
Reconstruction of multilayered and functional smooth muscle tissues remains a challenge nowadays. Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties. Inspired by the natural extracellular matrix, cellulose acetate electrospun nanofibers (NFs) were incorporated to chitosan/silk fibroin (CS/SF) cryogel scaffolds to address this problem in this work.
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