A decrease in urethral closure pressure is one of the primary causes of stress urinary incontinence in women. Atrophy of the urethral muscles is a primary factor in the 15 % age-related decline in urethral closure pressure per decade. Incontinence not only affects the well-being of women but is also a leading cause of nursing home admission.
View Article and Find Full Text PDFObjectives: Three-dimensional (3D) H-scan is a new ultrasound (US) technique that images the relative size of acoustic scatterers. The goal of this research was to evaluate use of 3D H-scan US imaging for monitoring early breast cancer response to neoadjuvant therapy using a preclinical murine model of breast cancer.
Materials And Methods: Preclinical studies were conducted using luciferase-positive breast cancer-bearing mice (n = 40).
Liver disease is increasing in prevalence across the globe. We present here a multiparametric ultrasound (mpUS) imaging approach for assessing nonalcoholic fatty liver disease (NALFD). This study was performed using rats (N = 21) that were fed either a control or methionine and choline deficient (MCD) diet.
View Article and Find Full Text PDFH-Scan ultrasound (US) is a new imaging technology that estimates the relative size of acoustic scattering objects and structures. The purpose of this study was to introduce a three-dimensional (3-D) H-scan US imaging approach for scatterer size estimation in volume space. Using a programmable research scanner (Vantage 256, Verasonics Inc, Kirkland, WA, USA) equipped with a custom volumetric imaging transducer (4 DL7, Vermon, Tours, France), raw radiofrequency (RF) data was collected for offline processing to generate H-scan US volumes.
View Article and Find Full Text PDFH-scan ultrasound (US) imaging (where the 'H' stands for Hermite) is a novel non-invasive, low cost and real-time technology. Like traditional US, H-scan US suffers from frequency-dependent attenuation that must be corrected to have acceptable image quality for tissue characterization. The goal of this research was to develop a novel attenuation correction method based on adaptive K-means clustering.
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