Publications by authors named "Haowei Tai"

A decrease in urethral closure pressure is one of the primary causes of stress urinary incontinence in women. Atrophy of the urethral muscles is a primary factor in the 15 % age-related decline in urethral closure pressure per decade. Incontinence not only affects the well-being of women but is also a leading cause of nursing home admission.

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  • The study evaluates the effectiveness of a new ultrasound technique called H-scan for monitoring breast cancer treatment by detecting cell death caused by chemotherapy.* -
  • Researchers used female mice with implanted breast cancer cells, imaging them with H-scan ultrasound and diffusion-weighted MRI over several days while administering a drug that induces apoptosis.* -
  • Results showed that H-scan imaging can indicate early changes in tumor response to treatment and has a strong correlation with MRI findings, suggesting it could be a valuable tool for clinicians.*
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  • H-scan ultrasound (US) is a high-resolution imaging technique that allows for detailed soft tissue analysis by capturing data in a 3D volume space, revealing subtle changes often missed by traditional methods.!
  • This study showcases a new 3-D H-scan US imaging technology using a matrix array transducer that measures the size of US scattering aggregates in various tissue types through innovative data collection procedures.!
  • Results indicate that 3-D H-scan US is significantly more sensitive in identifying different sizes of US scatterers compared to traditional B-mode US imaging, suggesting its potential for improved tissue characterization in clinical settings.!
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Objectives: Three-dimensional (3D) H-scan is a new ultrasound (US) technique that images the relative size of acoustic scatterers. The goal of this research was to evaluate use of 3D H-scan US imaging for monitoring early breast cancer response to neoadjuvant therapy using a preclinical murine model of breast cancer.

Materials And Methods: Preclinical studies were conducted using luciferase-positive breast cancer-bearing mice (n = 40).

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  • The study explores new ultrasound techniques to assess fatty liver disease, focusing on using the H-scan and Burr distribution to analyze tissue echo patterns.
  • Researchers tested these methods on 21 rats, comparing controls with those fed a diet leading to steatosis over several weeks.
  • Results showed that advanced ultrasound measures could accurately distinguish between normal and steatotic livers with 100% accuracy, validated by subsequent tissue analysis.
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Liver disease is increasing in prevalence across the globe. We present here a multiparametric ultrasound (mpUS) imaging approach for assessing nonalcoholic fatty liver disease (NALFD). This study was performed using rats (N = 21) that were fed either a control or methionine and choline deficient (MCD) diet.

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H-Scan ultrasound (US) is a new imaging technology that estimates the relative size of acoustic scattering objects and structures. The purpose of this study was to introduce a three-dimensional (3-D) H-scan US imaging approach for scatterer size estimation in volume space. Using a programmable research scanner (Vantage 256, Verasonics Inc, Kirkland, WA, USA) equipped with a custom volumetric imaging transducer (4 DL7, Vermon, Tours, France), raw radiofrequency (RF) data was collected for offline processing to generate H-scan US volumes.

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H-scan ultrasound (US) imaging (where the 'H' stands for Hermite) is a novel non-invasive, low cost and real-time technology. Like traditional US, H-scan US suffers from frequency-dependent attenuation that must be corrected to have acceptable image quality for tissue characterization. The goal of this research was to develop a novel attenuation correction method based on adaptive K-means clustering.

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