Purpose: To determine the sensitivity and specificity of different retinal imaging combinations for the diagnosis of choroidal neovascularization (CNV) in age-related macular degeneration.
Methods: Patients aged 50 years or older referred for suspicious recent-onset CNV related to age-related macular degeneration were prospectively included for 6 months. Data recorded included color fundus photographs (CFPs), spectral domain optical coherence tomography (SD-OCT), and fluorescein angiography (FA) images.
J Fr Ophtalmol
September 2010
Purpose: To measure the peripapillary retinal nerve fiber layer thickness (RNFL thickness) in normal children using optical coherence tomography (OCT) and evaluate the effects of several factors on RNFL thickness, in order to complete results of other studies on this topic.
Material And Method: One hundred and four eyes of 53 normal children were investigated using OCT (Stratus OCT 3, Carl Zeiss Meditec, Dublin, CA, USA) measuring the RNFL thickness. These 28 boys and 25 girls had a mean age of 9.
Purpose: To describe an unusual feature in myopic eyes responsible for visual loss, which we call a dome-shaped macula.
Design: Retrospective, observational case series.
Methods: After observing isolated cases of dome-shaped macula, we analyzed optical coherence tomography (OCT) scans of 140 highly myopic eyes present in our OCT database to find similar cases.
Purpose: To characterize the evolution of serous retinal detachment (SRD) combined with diabetic macular edema (DME) using optical coherence tomography (OCT).
Design: Observational retrospective case series.
Methods: In our institution, 64 eyes of 40 diabetic patients who had SRD combined with DME were studied.
Purpose: Full-thickness macular hole associated with diabetic macular oedema is a rare feature and its pathogenesis remains incompletely elucidated. We report the occurrence of a full-thickness macular hole, documented with optical coherence tomography (OCT), in a patient with diabetic cystoid macular oedema treated by intravitreal triamcinolone injections.
Case Report: A 48-year-old woman with refractory diabetic cystoid macular oedema underwent successive intravitreal triamcinolone injections, which were followed by a progressive thinning of the neurosensory retina at the fovea, and then by a full-thickness macular hole, associated with a perifoveal posterior hyaloid detachment, visible on OCT.
Purpose: To assess the optical coherence tomography (OCT) characteristics of spontaneously closed macular hole (MH).
Design: Retrospective observational case series.
Methods: Among 510 consecutive eyes examined for an MH before surgery, we retrospectively identified 14 eyes in which the MH closed spontaneously before the operation.
Purpose: To determine the natural evolution and surgical indications of myopic foveoschisis (MF), which are still poorly documented, and the factors that predict poor prognosis.
Design: Retrospective observational case series.
Methods: Twenty-nine operated and nonoperated cases of MF (29 eyes of 23 patients) were studied.
Objective: To describe the changes observed with optical coherence tomography in group 2A idiopathic juxtafoveolar retinal telangiectasis.
Methods: We retrospectively reviewed the medical records of 13 patients (25 eyes). All eyes underwent optical coherence tomography examination consisting of 6 radial scans, fundus color photography, and fluorescein angiography.
Purpose: To prospectively compare the efficacy and safety of 4 vs 2 mg intravitreal triamcinolone acetonide (TA) injection for diabetic macular edema.
Design: Interventional case series.
Patients: Thirty-two patients with diabetic macular edema unresponsive to laser photocoagulation.
Purpose: To evaluate prospectively the efficacy and safety of one intravitreal injection of 4 mg triamcinolone acetonide for refractory diffuse diabetic macular edema.
Methods: Seventeen patients with bilateral diabetic macular edema unresponsive to laser photocoagulation. In all patients, one eye was injected, and the other served as a control.
Aim: To investigate the relationship between the size of macular holes and the possible benefit of internal limiting membrane (ILM) peeling.
Methods: 84 consecutive cases of idiopathic macular hole followed up for at least 3 months were included in this retrospective study. Surgery comprised pars plana vitrectomy, peeling of any epiretinal membrane, 17% C2F6 (hexafluoroethane) gas filling and 10 days of positioning.
Cataract surgery requires a satisfactory degree of mydriasis throughout the entire operation. A phase I, open-labelled, randomised, cross-over trial was conducted in 18 healthy volunteers to compare mydriasis obtained with subsequent administration of phenylephrine 10% and tropicamide 0.5% eyedrops or a new insoluble-matrix retropalpebral ophthalmic insert containing 5.
View Article and Find Full Text PDFAims: To compare the values measured for retinal macular thickness with the first and last generations of the optical coherence tomograph (OCT1 and Stratus OCT, Zeiss, Humphrey Division).
Methods: This was a cohort study. 59 eyes were examined: 17 had a normal macula and 42 had a diabetic macular oedema.
Purpose: To use optical coherence tomography (OCT) to characterize the intraretinal changes associated with macular edema (ME) according to its etiology.
Design: Observational case series.
Methods: Seventy-eight eyes of 78 patients with ME were examined retrospectively by OCT, using the Humphrey 2000 OCT system (Humphrey Co.
Purpose: To study the vitreoretinal relationship in diabetic patients with and without diabetic macular edema (DME) using optical coherence tomography.
Design: Retrospective case-control study.
Methods: setting: Institutional practice.
Purpose: To assess the usefulness of optical coherence tomography (OCT) for better differential diagnosis of macular pseudoholes (MPH) and lamellar macular holes (LMH).
Design: Observational case series.
Methods: setting: Institutional practice.
Purpose: To develop a population model capable of describing the profile of the effect of intravitreal triamcinolone acetonide in the treatment of diabetic diffuse macular edema.
Methods: The results of 51 injections in 37 eyes (33 patients) with diffuse diabetic macular edema were studied, by using population pharmacokinetic-pharmacodynamic modeling, without triamcinolone concentration measurements. This approach was supported by the pharmacokinetic hypothesis that the intravitreal triamcinolone concentration decreases in accordance with an exponential biphasic equation.
Objective: To evaluate prospectively the efficacy and safety of 1 intravitreal injection of 4 mg of triamcinolone acetonide for refractory diffuse diabetic macular edema.
Design: Interventional case series.
Participants: Fifteen patients with bilateral diabetic macular edema unresponsive to laser photocoagulation.
Purpose: To evaluate the efficacy of intravitreal triamcinolone in refractory pseudophakic cystoid macular edema.
Design: A prospective, interventional case series.
Methods: Three eyes of three patients with longstanding pseudophakic cystoid macular edema following uncomplicated cataract surgery, refractory to any medication, were treated with 8 mg of intravitreal triamcinolone.
Purpose: To report the use of optical coherence tomography (OCT) for evaluation of diffuse diabetic macular edema (DME) before and after vitrectomy.
Design: Interventional case series.
Methods: A retrospective study was made of 15 consecutive eyes of 13 patients that had vitrectomy for diffuse DME and OCT preoperatively and postoperatively.
Purpose: To describe the characteristics and evolution of macular retinoschisis in high myopia observed by optical coherence tomography (OCT).
Design: A consecutive, retrospective, observational case series.
Methods: Twenty-one highly myopic eyes (mean refractive error, -15.
Purpose: To define the normal retinal thickness in healthy subjects using optical coherence tomography (OCT) mapping software and to assess the ability of OCT to detect early macular thickening in diabetic patients.
Methods: Six radial scans centered on the fixation point were done on 60 healthy eyes and 70 eyes of 35 diabetic patients without macular edema on biomicroscopy. Retinal thickness was measured automatically with OCT mapping software.
Objective: To assess the reproducibility of retinal thickness measurement using commercially available mapping software of optical coherence tomography (OCT).
Methods: Six radial scans, 6 mm long and centered on the fixation point, were performed on 10 eyes of 10 healthy volunteers and 10 eyes of 10 diabetic patients with clinically significant macular edema. Retinal thickness was measured automatically using the mapping software of OCT in the 9 macular Early Treatment Diabetic Retinopathy Study areas and in a central area 500 microm in diameter.