Prevalence, causes, and outcome at 2 years of age of newborn encephalopathy: population based study.

Objectives: To ascertain the prevalence of newborn encephalopathy in term live births, and also the underlying diagnoses, timing, and outcome at 2 years of surviving infants.

Design: Population based observational study.

Setting: North Pas-de-Calais area of France, January to December 2000.

[Fatal neonatal respiratory distress in Niemann-Pick C2 and prenatal diagnosis with mutations in gene HE1/NPC2].

Unlabelled: We report the fifth case of neonatal form of type C2 (NP-C2) Niemann-Pick disease with early and fatal respiratory distress. Eleven families presenting such cases are known to date in the world. Since December 2000, isolation of the underlying gene HE1/NPC2 and its mutations has allowed major advances in diagnosis.

[Congenital pulmonary lymphangiectasia revealed by cardiac arrest].

Unlabelled: Congenital pulmonary lymphangiectasia is a rare cause of respiratory distress in the neonatal period. Cardiac arrest may be its first manifestation.

Case Report: We report the case of a full term newborn who suffered at 30 min of life a sudden cardiac arrest.

[Use of double-lumen umbilical vein catheters in a neonatal intensive care unit].

Background: The aim of the study was to compare the success/failure rate and complications of insertion into the umbilical vein, of either double-lumen catheters (Charrière diameter 04, length 13 and 30 cm) or single-lumen catheters (Charrière diameter 05, length 40 cm) in a population of neonates admitted to a neonatal intensive care unit. The numbers of insertions of additional peripheral venous catheters were also compared.

Patients And Methods: The population was divided into two groups according to the severity of the respiratory failure.

[Motor deficiencies in children: for a nosologic clarification in epidemiological studies].

In order to clarify the epidemiological research on childhood motor deficiency in France there is a need to better differenciate the two terms used to define this pathology: the French term "infirmité motrice cérébrale" (IMC) and the English term "cerebral palsy" (CP). The distinction between IMC and CP is highlighted on the basis of clinical examples. IMC recovers motor deficiencies which are quite similar, however, it can be very difficult to control the variations in its use.

The analgesic effect of sucrose in full term infants: a randomised controlled trial.

Objective: To evaluate the effects of different sucrose concentrations on measures of neonatal pain.

Design: Randomised, double blind, placebo controlled trial of sterile water (control) or one of three solutions of sucrose--namely, 12.5%, 25%, and 50% wt/vol.