Publications by authors named "Haotian Meng"

3D-3D registration of facial models, has great advantages in personal individual identification in forensic medicine. However, orthodontic treatment has brought changes in facial soft and hard tissues, which has a potential effect in personal identification. The aim of the study was to explore whether orthodontic treatment affects 3D-3D facial recognition.

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  • About 10-20% of people with acute myeloid leukemia (AML) also have problems called extramedullary diseases (EMDs), which make their treatment a bit different.
  • In a study with 47 patients, results showed that those without EMDs had a better chance of complete remission (getting better) compared to those with EMDs after receiving a special treatment called CLL1 CAR-T therapy.
  • Overall, while people with EMDs had similar side effects and CAR-T cell responses as those without EMDs, their recovery and survival were slightly shorter, but the differences weren't big enough to be statistically important.
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Objectives: To investigate the application value of combining the Demirjian's method with machine learning algorithms for dental age estimation in northern Chinese Han children and adolescents.

Methods: Oral panoramic images of 10 256 Han individuals aged 5 to 24 years in northern China were collected. The development of eight permanent teeth in the left mandibular was classified into different stages using the Demirjian's method.

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  • The study explores the use of maxillary sinus measurements for sex estimation in forensic contexts, highlighting its potential due to the sinus's resilience in adverse conditions.
  • Using Cone-Beam Computed Tomography, the research analyzed data from 477 individuals in northwest China, employing various machine learning models, with Random Forest (RF) showing the best performance, especially in adults.
  • The results indicated a 77.78% accuracy rate for sex estimation in those over 18, with accuracy improving to 88.46% when including age as a factor, particularly for the 18-27 age group.
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Thrombosis and infection are two major complications associated with central venous catheters (CVCs), which significantly contribute to morbidity and mortality. Antifouling coating strategies currently represent an efficient approach for addressing such complications. However, existing antifouling coatings have limitations in terms of both duration and effectiveness.

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Background: Sex estimate is a key stage in forensic science for identifying individuals. Some anatomical structures may be useful for sex estimation since they retain their integrity even after highly severe events. However, few studies are focusing on the Chinese population.

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The Miao group is one of the representative Hmong-Mien-speaking populations and primarily scattered in southern China and Southeast Asia, which has experienced massive migrations in history and thus forms distinctive evolutionary genetics. Yet, the genetic explorations of Miao group are relatively limited based on complete mitochondrial genome (mitogenome), especially for the Miao group from Yunnan Province (YNM). Here, we sequenced complete mitogenomes of 132 Miao individuals from Yunnan Province using massively parallel sequencing method.

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  • - The adoption of microfluidic technology in forensic medicine has increased over the past 20 years due to its benefits like low cost, speed, and minimal contamination.
  • - A bibliometric analysis was performed to explore the relationship between forensic science and microfluidics by examining literature from 1989 to 2022, particularly focusing on forensic genetics.
  • - This review assesses the current use of microfluidic technology in forensics, while also discussing the challenges faced and future trends in forensic genetics.
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Sex estimation is very important in forensic applications as part of individual identification. Morphological sex estimation methods predominantly focus on anatomical measurements. Based on the close relationship between sex chromosome genes and facial characterization, craniofacial hard tissues morphology shows sex dimorphism.

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To realize continuous real-time monitoring of the large-scale internal strain field of coal and rock mass, a bidirectional strain sensor based on FBGs encapsulated using a hollow cylindrical steel tube was designed. The sensor's structural parameters were optimized through unidirectional loading, and the strain change laws of the sensor were analyzed under unidirectional and bidirectional loading conditions, in which the stress-strain fitting curves of the sensor and the relationships of the strain in the vertical and horizontal directions were obtained under different lateral pressure loading conditions. A similar theoretical model was established to verify the accuracy of the linear relationship between the surrounding rock stress and the strain measured by the sensor system.

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Unsaturated polyester resins (UPRs) are expansively used in different applications and recycling the significant amounts of UPR waste is still a universal problem. Vitrimerization is a feasible, environmental-friendly, cost effective, and operative method, which can be used for recycling the crosslinked UPRs. In this method, the thermoset permanent network is changed into a dynamic network similar to the vitrimer-type polymers.

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Co-separation studies between surnames and Y chromosome genetic markers are beneficial to revealing population migrations, surname origins, population formation histories and forensic familial searching. Genetic distributions of 27 Y-STRs in Chinese four surnames (Li, Lin, Chen and Huang) from Zhanjiang Han population were investigated. Meanwhile, we tried to develop a decision tree model for surname predictions based on Y-STR haplotypes.

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Short tandem repeats (STRs) play an essential role in forensic genetics due to their high degree of polymorphisms, wide distributions and easy detection method. In this study, allelic frequencies and forensic statistical parameters of the 19 autosomal STR loci in a Kazak ethnic group were calculated, and its genetic relationships with reference populations were assessed in order to understand population structure better and enrich population genetic data for forensic practice in Chinese Kazak ethnic group. There were 226 identified alleles with the corresponding allelic frequencies ranging from 0.

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Based on the official data modeling, this paper studies the transmission process of the Corona Virus Disease 2019 (COVID-19). The error between the model and the official data curve is quite small. At the same time, it realized forward prediction and backward inference of the epidemic situation, and the relevant analysis help relevant countries to make decisions.

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Background: Individual identification is one of the most important tasks in the field of forensic genetics. Insertion/Deletion (InDel) polymorphism marker has been a promising marker for individual identification. However, a part of InDel loci in commonly used commercial kit show low polymorphisms in Chinese populations.

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Mitochondrial DNA (mtDNA) has been widely employed as one tool for the studies of human migration and phylogenetic evolution owing to the characteristics of its lack of recombination and matrilineal inheritance. In this study, we analyze genetic distributions of 60 mtDNA markers in 126 unrelated individuals of Southern Shaanxi Han population and classify their haplogroups. Genetic distribution comparisons between Southern Shaanxi Han and other populations from different continents are conducted based on the same mtDNA markers.

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Insertion and deletion markers (InDels) have gained considerable attentions in population genetics and forensic research. In this study, we investigated genetic distributions of 30 InDels in Gansu Yugur and Guizhou Miao groups and evaluated their forensic application values. Genetic relationship analyses between Gansu Yugur, Guizhou Miao groups and other published populations were conducted based on these 30 InDels.

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Prior to implementing a new kit into application, developmental validation should be conducted to demonstrate the robustness and applicability of the kit. In this study, 24 Y-STR loci from the AGCU Y SUPP STR kit were tested including 11 loci overlapping with other commercial kits (DYS385a/b, DYS635, DYS533, DYS481, DYS549, DYS460, DYS527a/b, DYS522, and DYS444) and 13 new loci (DYS531, DYS630, DYS622, DYS552, DYS510, DYS459a/b, DYS446, DYS443, DYS587, Y-GATA-A10, DYS520, and DYS557). Developmental validation including PCR-related studies, sensitivity, stability, and species specificity studies were conducted.

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China is a multinational country composed of 56 ethnic groups of which the Han Chinese accounts for 91.60%. Qinghai Province is located in the northeastern part of the Qinghai-Tibet Plateau, has an area of 72.

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Short tandem repeats (STRs) with a high level of polymorphisms and convenient detection method play an indispensable role in human population and forensic genetics. Recently, we detected the 21 autosomal non-combined DNA index system (non-CODIS) STR loci in a Kyrgyz ethnic group, calculated their forensic parameters and analysed its genetic relationships with reference populations from China. In total, 168 alleles were observed at 21 non-CODIS STRs with corresponding allelic frequencies from 0.

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We investigated the allelic frequencies and forensic descriptive parameters of 23 autosomal short tandem repeat loci in a randomly selected sample of 1218 unrelated healthy Uyghur individuals residing in the Xinjiang Uyghur Autonomous Region, northwest China. A total of 281 alleles at these loci were identified and their corresponding allelic frequencies ranged from 0.0004 to 0.

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We analyzed the genetic polymorphisms of 15 autosomal and 10 Y-chromosomal STR loci in 214 individuals of Han population from Southern Shaanxi of China and studied the genetic relationships between Southern Shaanxi Han and other populations. We observed a total of 150 alleles at 15 autosomal STR loci with the corresponding allelic frequencies ranging from 0.0023 to 0.

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  • - A study analyzed genetic diversity in 125 blood samples from the Bai group in Yunnan, China, using 30 insertion/deletion loci, revealing a range of heterozygosity between 0.1520 and 0.5680.
  • - The results showed no significant deviations from Hardy-Weinberg equilibrium, indicating reliability, and suggested that these loci are effective for paternity testing and personal identification in forensic cases, with high cumulative probabilities.
  • - Additionally, the Bai group exhibited close genetic relationships with Tibetan, Yi, and Han groups, but further DNA genotyping is recommended for a deeper understanding of Bai ethnicity's genetic background.
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