Publications by authors named "Haorong Gu"
Article Synopsis
- * The study evaluated the effectiveness of different recombinant proteins (SAG2, GRA6, GRA7) in an ELISA test for diagnosing Toxoplasma infection in cats, highlighting the need for accurate diagnostic tools.
- * Results indicated that GRA7 was the most sensitive antigen for detecting infection in cats, while another protein, GRA3, also showed promise in identifying infected animals when produced through a plant-based system.
Introduction: Reverse genetics has become an indispensable tool to gain insight into the pathogenesis of viruses and the development of vaccines. The yeast-based synthetic genomics platform has demonstrated the novel capabilities to genetically reconstruct different viruses.
Methods: In this study, a transformation-associated recombination (TAR) system in yeast was used to rapidly rescue different strains of feline infectious peritonitis virus, which causes a deadly disease of cats for which there is no effective vaccine.
Gamma interferon (IFN-γ)-induced innate immune responses play important roles in the inhibition of infection. It has been reported that IFN-γ stimulates non-acidification-dependent growth restriction of in HeLa cells, but the mechanism remains unclear. Here, we found that γ-aminobutyric acid (GABA) receptor-associated protein-like 2 (GABARAPL2) plays a critical role in parasite restriction in IFN-γ-treated HeLa cells.
View Article and Find Full Text PDFObjective: To study the Chinese ancient five-element theory, one of the philosophical foundations of Traditional Chinese Medicine (TCM) theory construction, from the perspective of comtemporary cognitive science, and to reveal the important functions of five-element theory in the construction of TCM theory.
Methods: The basic effects of five-element theory in the construction of TCM theory are intensively expounded and proved from the following aspects: embodiment of five-element theory in cognizing the world, quasi axiom of five-element theory in essence, classification thery of family resemblance and deductive inference pattern of five-element theory, and the openness and expansibility of five-element theory.
Results: If five-element theory is considered a cognitive pattern or cognitive system related to culture, then there should be features of cognitive embodiment in the cognitive system.