Publications by authors named "Haoquan Cai"
Article Synopsis
- First-line and second-line immunotherapy using PD-1 inhibitors both enhance overall survival in advanced oesophageal squamous cell cancer (ESCC), as shown in a registry study of 167 patients.
- The study found that median progression-free survival (PFS) was significantly greater for patients receiving PD-1 inhibitors first (7.1 months) compared to those who received them second (4.1 months).
- However, overall survival rates were similar for both groups, with median overall survival at 13.5 months for first-line treatment and 14.1 months for second-line, indicating no significant difference.
Objectives: To compare the effects of an erlotinib-based targeted dual agent with erlotinib alone in previously treated patients with advanced non-small lung cancer (NSCLC).
Patients And Methods: The PubMed and Embase databases and the Cochrane Central Register of Controlled Trials were searched for publications between January 2005 and March 2016. Hazard ratios (HRs) with their 95% confidence intervals (CIs), or data for calculating HRs with 95% CIs were derived.
Objectives: To investigate the effects of angiogenesis inhibitors in the treatment of patients with advanced or recurrent ovarian cancer, a meta-analysis was performed and overall survival (OS), progression-free survival (PFS), and toxicity were assessed.
Patients And Methods: The PubMed and Embase databases, and the Cochrane Central Register of Controlled Trials were searched for publications between January 2000 and June 2015. Hazard ratios (HRs) with their 95% confidence intervals (CIs), or data for calculating HRs with 95% CIs were derived.
A meta-analysis of all relevant randomized controlled trials (RCTs) was performed to assess the role of maintenance therapy with either a continuation or a switch strategy in the treatment of non-small-cell lung cancer and to investigate improvement in overall survival (OS) and progression-free survival (PFS). Depending on the tumor histologic type (squamous or nonsquamous), OS and PFS were also investigated. We used electronic databases to search for publications reporting RCTs comparing maintenance therapy and placebo or observation from January 1990 to March 2012.
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