A Wavy Multiple Tm(III)-Containing Open Wells-Dawson Silicotungstate: Synthesis, Structure, and Catalytic Application.

A Tm(III)-rich silicotungstate Na{Tm(HO)[Tm(HO)(SiWO)]}·35HO () based on the open Wells-Dawson-type [SiWO] building unit was synthesized by the reaction of Na[α-SiWO]·18HO, itaconic acid, and TmCl in a HAc/NaAc buffer solution. Five kinds of Tm(III) ions were found in this compound and further linked the {TmSiW} subunit to form an interesting wavy 1D chain structure, which achieved the introduction of more lanthanide (Ln) ions into the [SiWO] unit for the first time. contains multiple exposed Tm-metal active sites, making it an efficient catalyst for the acetalization of 2-aminobenzamides/2-aminobenzenesulphonamides with aldehydes.

Single-cell RNA sequencing reveals the contribution of smooth muscle cells and endothelial cells to fibrosis in human atrial tissue with atrial fibrillation.

Aims: Atrial fibrillation (AF) has high mortality and morbidity rates. However, the intracellular molecular complexity of the atrial tissue of patients with AF has not been adequately assessed.

Methods And Results: We investigated the cellular heterogeneity of human atrial tissue and changes in differentially expressed genes between cells using single-cell RNA sequencing, fluorescence in situ hybridization, intercellular communication, and cell trajectory analysis.

Mixed Carboxylate Ligands Bridging Tetra-Pr-Encapsulated Antimonotungstate: Syntheses, Structure, and Catalytic Activity for Imidazoles Synthesis.

Multinuclear Pr-containing antimonotungstate [Pr(HO)WO(mal)(OAc)(αSbWO)] (, mal = malate anion, OAc = acetate anion), bridged by organic carboxylic acid, was synthesized through a one-pot assembly reaction and structurally characterized. is composed of four [αSbWO] fragments fused together by an organic-inorganic hybrid central [Pr(HO)WO(mal)(OAc)] cluster core through 24 μ-O atoms. Notably, the central cluster comprises unprecedented decanuclear Pr(HO)WO jointly decorated by two types of carboxylic acid ligands.

Dy/Ho-encapsulated tartaric acid-functionalized tungstoantimonates: heterogeneous catalysts for isoindolinone synthesis.

Two novel rare earth-substituted tungstoantimonates [HN(CH)]Na[Dy(HO)(tar)(SbWO)]·40HO (DySbW) and [HN(CH)]Na[Ho(HO)(tar)(SbWO)]·25HO (HoSbW) (Htar = tartaric acid) were synthesized. The -polyanions are alternately linked by {Na(HO)} clusters and DL-tar ligands to form 1D chains. Notably, HoSbW exhibits excellent catalytic activity and high stability for the synthesis of isoindolinones using EtOH as a green solvent.

Counteractive effects of predator invasion and habitat destruction on predator-prey systems.

Alien species invasion and habitat destruction are among the primary threats to native animal communities, particularly for native predator-prey systems. However, when predator invasion and habitat destruction co-occur, it remains unclear whether their respective threats to native systems compensate each other or accumulate, as well as how these effects respond to the different characteristics of predator invasion and habitat destruction. In this study, we developed a spatially explicit simulation model with one prey species and one predator species and exposed it to invasive predators and habitat destruction with different properties.

Global soil respiration estimation based on ecological big data and machine learning model.

Soil respiration (Rs) represents the greatest carbon dioxide flux from terrestrial ecosystems to the atmosphere. However, its environmental drivers are not fully understood, and there are still significant uncertainties in soil respiration model estimates. This study aimed to estimate the spatial distribution pattern and driving mechanism of global soil respiration by constructing a machine learning model method based on ecological big data.

Exploration of the mechanism of Traditional Chinese Medicine for anxiety and depression in patients with diarrheal irritable bowel syndrome based on network pharmacology and meta-analysis.

Background: The efficacy of Chinese herbal medicine (CHM) in managing irritable bowel syndrome with diarrhea (IBS-D) accompanied by anxiety and depression remains uncertain. Thus, a systematic review was carried out employing meta-analysis and network pharmacology to ascertain the efficacy and underlying mechanisms of CHM therapy.

Methods: By conducting a systematic review, including literature search, screening, and data extraction, we identified 25 randomized controlled trials to assess CHM's effectiveness in treating irritable bowel syndrome alongside anxiety and depression.

Pathological mechanisms and future therapeutic directions of thrombin in intracerebral hemorrhage: a systematic review.

Intracerebral hemorrhage (ICH), a common subtype of hemorrhagic stroke, often causes severe disability or death. ICH induces adverse events that might lead to secondary brain injury (SBI), and there is currently a lack of specific effective treatment strategies. To provide a new direction for SBI treatment post-ICH, the systematic review discussed how thrombin impacts secondary injury after ICH through several potentially deleterious or protective mechanisms.

Serum N-glycomic profiling identifies candidate biomarker panels for assessing coronary artery stenosis severity.

Stenosis severity may escalate over the course of coronary artery disease (CAD), increasing the risk of death for the patient. Conventionally, the assessment of stenosis degree relies on invasive coronary angiography (ICA), an invasive examination unsuitable for patients in poor physical condition or those with contrast allergies and one that imposes a psychological burden on patients. Although abnormal serum N-glycan profiles have exhibited robust associations with various cardiovascular diseases, including CAD, their potential in diagnosing CAD stenosis remains to be determined.

Hemostasis after transradial coronary intervention by rotary compression device with sterile gauze is associated with more adverse events: a retrospective study.

Objective: We investigated the relationship between using a rotary compression device (RCD) with or without sterile gauze and adverse events in transradial access (TRA) for coronary intervention.

Methods: In this study involving 933 patients at Yueyang Hospital, we recorded TRA-related adverse events, such as bleeding, forearm hematoma, swollen palms, radial artery occlusion (RAO) and others. Logistic regression was applied to assess the association.

Research on motion recognition based on multi-dimensional sensing data and deep learning algorithms.

Motion recognition provides movement information for people with physical dysfunction, the elderly and motion-sensing games production, and is important for accurate recognition of human motion. We employed three classical machine learning algorithms and three deep learning algorithm models for motion recognition, namely Random Forests (RF), K-Nearest Neighbors (KNN) and Decision Tree (DT) and Dynamic Neural Network (DNN), Convolutional Neural Network (CNN) and Recurrent Neural Network (RNN). Compared with the Inertial Measurement Unit (IMU) worn on seven parts of body.

Plant immune inducer ZNC promotes rutin accumulation and enhances resistance to Botrytis cinerea in tomato.

Gray mold is a destructive disease caused by Botrytis cinerea, a pervasive plant pathogen, which poses a threat to both tomato growth and postharvest storage. The utilization of induced resistance presents a potential strategy for combating plant pathogenic attacks. ZNC (zhinengcong), an extract derived from the endophytic fungus Paecilomyces variotii, has been discovered to play a vital role in preventing diverse forms of bacterial infections.

Revisiting the role of the complement system in intracerebral hemorrhage and therapeutic prospects.

Intracerebral hemorrhage (ICH) is a stroke subtype characterized by non-traumatic rupture of blood vessels in the brain, resulting in blood pooling in the brain parenchyma. Despite its lower incidence than ischemic stroke, ICH remains a significant contributor to stroke-related mortality, and most survivors experience poor outcomes that significantly impact their quality of life. ICH has been accompanied by various complex pathological damage, including mechanical damage of brain tissue, hematoma mass effect, and then leads to inflammatory response, thrombin activation, erythrocyte lysis, excitatory amino acid toxicity, complement activation, and other pathological changes.

The Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients with Type 2 Diabetes.

Background: Patients with type 2 diabetes have poor medication adherence. Medication literacy is one of the influencing factors of medication adherence among patients with type 2 diabetes. However, the mechanism by which medication literacy affects medication adherence among patients with type 2 diabetes is unclear.

Association between medication literacy and blood pressure control among hypertensive patients.

Aim: This study aimed to explore the association between medication literacy and blood pressure control among hypertensive patients.

Background: Blood pressure control is a challenge for global health systems. Medication literacy is essential for medication self-management in hypertensive patients and a basis for managers to develop comprehensive intervention strategies for hypertension medication use.

Development and psychometric assessment of self-reported patient medication safety scale (SR-PMSS).

Objectives: Patient medication safety can affect their clinical outcomes and plays an important role in patient safety management. However, few tools have been developed to assess patient medication safety. This study aimed to develop and validate the self-reported patient medication safety scale (SR-PMSS).

regulates the accumulation of lycopene, fruit shape, and resistance to in tomato.

Fruit lycopene, shape, and resistance are essential traits in vegetables whose final product is fruit, and they are also closely related to and strictly regulated by multiple transcription factors. Lycopene, which cannot be synthesized by the human body and can only be ingested from the outside, was important in maintaining human health. During fruit ripening and post-harvest, tomato plants face a variety of biotic or abiotic stresses, which might inflict great damage to fruit quality due to its flat shape and pointed tip during storage and transportation.

Exploring the pharmacological mechanism of Naoxueshu oral liquid in the treatment of intracerebral hemorrhage through weighted gene co-expression network analysis, network pharmacological and experimental validation.

Background: Intracerebral hemorrhage (ICH) is a life-threatening stroke subtype with high rates of disability and mortality. Naoxueshu oral liquid is a proprietary Chinese medicine that absorbs hematoma and exhibits neuroprotective effects in patients with ICH. However, the underlying mechanisms remain obscure.

Protective effect of Xingnaojing injection on ferroptosis after cerebral ischemia injury in MCAO rats and SH-SY5Y cells.

Ethnopharmacological Relevance: Xingnaojing（XNJ）injection is a traditional Chinese medicine injection with neuroprotective effect, which has been widely used in the treatment of stroke for many years.

Aim Of The Study: This study aimed to explore the potential mechanism of XNJ in cerebral ischemia mediated by ferroptosis using proteomics and in vivo and in vitro experiments.

Materials And Methods: After the rat model of middle cerebral artery occlusion (MCAO) was successfully established, they were randomly divided into model, XNJ, and deferoxamine (DFO) group.

Psychometric properties and validation of the revised Chinese Medication Literacy Scale for Hypertensive Patients (C-MLSHP-R).

Background: Medication literacy is one of the key indicators that can affect the self-management of medications and medication safety. This study aimed to revise the Chinese Medication Literacy Scale for hypertensive patients (C-MLSHP) and test the reliability and validity of the revised scale.

Methods: We revised the C-MLSHP by several methods, i.

Network Pharmacology and Bioinformatics Methods Reveal the Mechanism of Berberine in the Treatment of Ischaemic Stroke.

Aim: To elucidate the mechanism of action of berberine on ischaemic stroke based on network pharmacology, bioinformatics, and experimental verification.

Methods: Berberine-related long noncoding RNAs (lncRNAs) were screened from public databases. Differentially expressed lncRNAs in ischaemic stroke were retrieved from the Gene Expression Omnibus (GEO) database.

Asymmetrically Doping a Platinum Atom into a Au Nanocluster for Changing the Electron Configuration and Reactivity in Electrocatalysis.

It is an obstacle to precisely manipulate a doped heteroatom into a desired position in a metal nanocluster. Herein, we overcome this difficulty to obtain Pt Au (SCH Ph Bu) and Pt Au (SCH Ph Bu) nanoclusters via controllably doping Pt atoms into the kernels of Au (SCH Ph Bu) . We reveal that asymmetrical doping of one Pt atom into either of the cores of Au (SCH Ph Bu) elevates the relative energy of the HOMO (highest occupied molecular orbital) accompanied by one valence electron loss of Pt Au (SCH Ph Bu) , compared to Au (SCH Ph Bu) with 14 electrons, while symmetrical doping of two Pt atoms into the cores of Au (SCH Ph Bu) narrows the HOMO-LUMO gap (LUMO: lowest unoccupied molecular orbital) of Pt Au (SCH Ph Bu) with two valence electrons less.

A Compressed Sensing Measurement Matrix Construction Method Based on TDMA for Wireless Sensor Networks.

Compressed sensing theory has been widely used for data aggregation in WSNs due to its capability of containing much information but with light load of transmission. However, there still exist some issues yet to be solved. For instance, the measurement matrix is complex to construct, and it is difficult to implement in hardware and not suitable for WSNs with limited node energy.