Publications by authors named "Haopeng Hong"
Background: Colorectal cancer (CRC) is a serious global health burden because of its high morbidity and mortality rates. Hypoxia and massive lactate production are hallmarks of the CRC microenvironment. However, the effects of hypoxia and lactate metabolism on CRC have not been fully elucidated.
View Article and Find Full Text PDFBackground: Mucinous adenocarcinoma (MAC) is a unique subtype of colorectal cancer and its prognostic value remains controversial. This study aimed to compare the clinicopathological characteristics and prognostic differences between patients with MAC and non-mucinous adenocarcinoma (NMAC).
Methods: 674 patients with NMAC, 110 patients with adenocarcinoma with mucinous component (ACWM) and 77 patients with MAC between 2016-2019 were enrolled in the study.
Epidemiology and early screening strategies for colorectal cancer in China.
Chin J Cancer Res
December 2023
Article Synopsis
- China leads the world in new colorectal cancer cases and deaths, with a worrying rise in early-onset cases, indicating a need for better screening and prevention efforts.
- High-quality colonoscopy is the gold standard for screening CRC, and combining risk assessment with a two-step strategy has proven effective in identifying at-risk individuals.
- Future CRC screening efforts should focus on personalizing and standardizing approaches, starting from high-risk screening to follow-ups, to enhance efficiency and effectiveness.
Colorectal cancer (CRC) is a deadly form of cancer worldwide. Patients with locally advanced rectal cancer and metastatic CRC have a poor long-term prognosis, and rational and effective treatment remains a major challenge. Common treatments include multi-modal combinations of surgery, radiotherapy, and chemotherapy; however, recurrence and metastasis rates remain high.
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