Publications by authors named "Haoning Sun"

Article Synopsis
  • - Patients with coronary artery disease (CAD) need antiplatelet drugs like clopidogrel to prevent blood clots, but genetic variations can affect how well they respond to these medications.
  • - A study with 935 CAD patients looked at 19 specific genetic variants (SNPs) to see how they relate to the risk of recurrent ischemic events, finding that a polygenic model with 6 SNPs could more effectively predict drug response.
  • - The research showed that patients with 7 or more risk alleles had a significantly higher risk of ischemic events compared to those with 6 or fewer, suggesting the model could improve treatment strategies for CAD patients.
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Objective: To investigate the effect of statins on the severity of coronary artery lesion in patients with coronary heart disease, and to analyze the risk factors of clinical prognosis.

Methods: A retrospective cohort study was conducted. The clinical data of 156 patients with coronary heart disease and completed the second re-examination of coronary CT angiography (CCTA) who were admitted to the department of cardiovascular medicine of Peking University People's Hospital from January 2017 to December 2021 were collected.

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