Publications by authors named "Haoming Kuang"
Article Synopsis
- - The study developed an artificial neural network (ANN) model to predict osteosarcoma (OS) cases based on genetic characteristics, identifying 467 differentially expressed genes (DEGs) with various functions and pathways associated with immune responses and infections.
- - A PPI network analysis revealed the top ten hub DEGs, and the ANN model was validated for accuracy and reliability in predicting OS based on test samples.
- - The research also explored the interaction between immune cells and critical DEGs, analyzing the expression of the most significant two DEGs (YES1 and MFNG) in OS compared to normal tissues, highlighting their potential role in early diagnosis and treatment of the disease.
Background: To aim of this study is to assess the mechanism through which Desertliving Cistanche modulates the PI3K/AKT signaling pathway in the treatment of hyperlipidemic osteoporosis in ovariectomized rats.
Methods: We randomly assigned specific-pathogen-free (SPF) rats into five groups (n = 10 per group). The normal control group received a standard diet, while the model group, atorvastatin group, diethylstilbestrol group, and treatment group were fed a high-fat diet.
Background: Rehabilitation after total knee arthroplasty (TKA) has become an indispensable part of the treatment strategy for degenerative joint disease. Despite some current research demonstrating efficacy of transcutaneous electrical acupoint stimulation (TEAS) for post-TKA rehabilitation, the evidence is not conclusive.
Objective: To systematically assess the evidence supporting TEAS for rehabilitation after TKA.
Circadian rhythms are internal 24-h intrinsic oscillations that are present in essentially all mammalian cells and can influence numerous biological processes. Cardiac function is known to exhibit a circadian rhythm and is strongly affected by the day/night cycle. Many cardiovascular variables, including heart rate, heart rate variability (HRV), electrocardiogram (ECG) waveforms, endothelial cell function, and blood pressure, demonstrate robust circadian rhythms.
View Article and Find Full Text PDFL. is used in traditional Chinese medicine for its anti-diabetic activity; however, the part of the hypoglycemic activity and related active metabolites are still not fully clarified. In this study, the metabolites in the roots, leaves, twigs, and fruits extracts (70% ethanol extracts) were systematically identified, and their hypoglycemic activity was evaluated by the high-fat diet/streptozotocin-induced 2 diabetes mellitus (T2D) mouse model.
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