Publications by authors named "Haoke Chen"
Cultured meat needs edible bio-scaffolds that provide not only a growth milieu for muscle and adipose cells, but also biomimetic stiffness and tissue-sculpting topography. Current meat-engineering technologies struggle to achieve scalable cell production, efficient cell differentiation, and tissue maturation in one single culture system. Here we propose an autoclaving strategy to transform common vegetables into muscle- and adipose-engineering scaffolds, without undergoing conventional plant decellularization.
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- Cell encapsulation technology faces challenges with existing methods; microfluidics can harm cells, while conventional electrospray suffers from instability and breakage at high throughput.
- A new superimposed electric field (SEF)-enhanced electrospray method improves stability and biocompatibility, allowing for fast production of around 300 core-shell capsules per second.
- This method leads to significant advancements, such as increasing iPSC growth by 92 times compared to traditional cultures and creating liver capsules for modeling liver diseases, showing promise for clinical applications like transplantation and drug screening.*