Publications by authors named "Haokai Qin"
Background: Combined valve and coronary surgery is a commonly performed surgical technique for treating coexisting valvular and coronary artery disease. This study aims to investigate the effect of reducing the duration of cardiopulmonary bypass by utilizing the off-pump coronary artery bypass grafting (OPCABG) technique on the short-term prognosis of patients.
Methods: In this retrospective cohort study, 884 patients were divided into groups undergoing OPCABG or on-pump CABG combined with valve surgery based on the CABG technique.
Complex role of neutrophils in the tumor microenvironment: an avenue for novel immunotherapies.
Cancer Biol Med
September 2024
Neutrophils, which originate from the bone marrow and are characterized by a segmented nucleus and a brief lifespan, have a crucial role in the body's defense against infections and acute inflammation. Recent research has uncovered the complex roles of neutrophils as regulators in tumorigenesis, during which neutrophils exhibit a dualistic nature that promotes or inhibits tumor progression. This adaptability is pivotal within the tumor microenvironment (TME).
View Article and Find Full Text PDFBackground: Postoperative atrial fibrillation (POAF) has long been associated with poor perioperative outcomes after coronary artery bypass grafting (CABG). In this study, we aimed to investigate the effect of prolonged POAF durations on perioperative outcomes of CABG.
Methods: This retrospective cohort study examined CABG patients enrolled at Beijing Anzhen Hospital from January 2018 to September 2021.
Article Synopsis
- Postoperative atrial fibrillation (POAF) is a frequent complication after coronary artery bypass grafting (CABG), but its underlying mechanisms are not well understood, leading to a lack of effective prevention measures.
- The study utilized targeted metabolomics to analyze pericardial fluid and serum samples from CABG patients, discovering nine metabolites that differ between those with and without POAF.
- A predictive model using four metabolites (aceglutamide, ornithine, methionine, and arginine) was developed and showed strong potential in predicting POAF, showcasing the value of metabolomics in understanding and anticipating this condition.