Case series: Hearing loss in neuromyelitis optica spectrum disorders.

Background: Aquaporin 4 (AQP4)- and myelin oligodendrocyte glycoprotein (MOG)-associated neuromyelitis optica spectrum disorders (NMOSD) are thought to primarily affect the central nervous system (CNS). However, emerging evidence suggests that there are extra-CNS manifestations of NMOSD, including myopathies, gastrointestinal dysfunction, renal involvement and adverse pregnancy outcomes. METHODS: Three patients who reported hearing loss during a NMOSD relapse were identified through a retrospective case review.

A case of GFAP-astroglial autoimmunity presenting with reversible parkinsonism.

Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a newly recognized autoimmune central nervous system (CNS) inflammatory disorder, presenting with an array of neurological symptoms in association with autoantibodies against GFAP, a hallmark protein expressed on astrocytes. Limited knowledge is available on the disease pathogenesis and clinical outcome. Here, we report a case of autoimmune GFAP astrocytopathy presenting with encephalomyelitis and parkinsonism.

Training in ChiRunning to reduce blood pressure: a randomized controlled pilot study.

Background: People with prehypertension (120-130/80-90 mmHg) are at increased risk of progressing to hypertension. Recommendations for prehypertension include engaging in regular physical activity. We aimed to assess feasibility and acceptability and collect preliminary outcome data on ChiRunning for people with elevated blood pressure.

Effects of Form-Focused Training on Running Biomechanics: A Pilot Randomized Trial in Untrained Individuals.

Objective: To investigate the changes in running biomechanics after training in form-focused running using ChiRunning versus not-form focused training and self-directed training in untrained individuals.

Design: Pilot study-randomized controlled trial.

Setting: Research institution with tertiary care medical center.