Alleviating effects of pea peptide on oxidative stress injury induced by lead in PC12 cells Keap1/Nrf2/TXNIP signaling pathway.

Background: Lead poisoning causes an oxidative stress response - a key "bridge" connecting various pathways - in the human body. Oxidative stress usually implies an imbalance between pro-oxidants and antioxidants. Moreover, Nrf2, Keap1, and TXNIP proteins play an essential role in oxidative stress.