Publications by authors named "Hao-wen Zhu"

Article Synopsis
  • - The photocatalytic reduction of CO into useful chemicals and fuels is gaining attention for its environmental and energy benefits, with metal halide perovskites (MHPs) being promising photocatalysts due to their optoelectronic properties.
  • - However, MHPs face challenges like instability, high electron-hole recombination, and limited active sites, driving research to improve their effectiveness.
  • - The review discusses the principles of photocatalysis, evaluates MHP characteristics, and highlights strategies for enhancement, while also addressing the challenges and future directions needed for practical applications.
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Photocatalytic reduction of CO (PCR) technology offers the capacity to transmute solar energy into chemical energy through an eco-friendly and efficacious process, concurrently facilitating energy storage and carbon diminution, this innovation harbors significant potential for mitigating energy shortages and ameliorating environmental degradation. Bismuth tungstate (BiWO) is distinguished by its robust visible light absorption and distinctive perovskite-type crystal architecture, rendering it highly efficiency in PCR. In recent years, numerous systematic strategies have been investigated for the synthesis and modification of BiWO to enhance its photocatalytic performance, aiming to achieve superior applications.

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Hippocampal neuronal apoptosis is a devastating consequence of cardiac arrest (CA) and subsequent cardiopulmonary resuscitation (CPR). In this study, we assessed the contribution of cytotoxic T lymphocyte (CTL)-derived toxic mediator granzyme B (Gra-b) to the hippocampal neuronal apoptosis following CA/CPR in rats. Rats that experienced CA/CPA presented with cytosomal shrinkage, dense cytoplasm, and intensive eosinophilic staining in the CA1 region of dorsal hippocampus.

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Little is known about the diversity and succession of indigenous microbial community during debromination of polybrominated diphenyl ethers (PBDEs). This study examined the diversity and dynamics of microbial community structure in eight saline (mangrove and marine) and freshwater sediment microcosms exhibiting different debrominating capabilities for hexa-BDE 153, a common congener in sediments, using terminal restriction fragment length polymorphism (T-RFLP) and clone library analyses. The results showed that microbial community structure greatly differed between the saline and freshwater microcosms, likely leading to distinct variations in their debrominating capabilities and pathways.

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Article Synopsis
  • The study investigates how two mangrove plant species, Excoecaria agallocha and Kandelia obovata, absorb toxic pollutants from wastewater under different tidal conditions.
  • The results show that most pollutants, like PAHs and PBDEs, were captured in iron (Fe) plaques on the roots rather than in the plants themselves, with E. agallocha outperforming K. obovata in removing these pollutants.
  • Additionally, the effectiveness of pollutant immobilization in the Fe plaques was significantly influenced by the frequency of tidal flushing, with more frequent flushing leading to better pollutant capture.
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Aim: To determine the in vitro and in vivo bioactivity of recombinant human endostatin (rhEndostatin) and to analyze its pharmacokinetics and immunogenicity in rhesus monkeys and patients.

Methods: The physical chemical characteristics of rhEndostatin were detected according to Pharmacopoeia of the People's Republic of China (2005 edition, part III). Its in vitro and in vivo bioactivities were assayed via proliferation-inhibition on human umbilical vein endothelial cells and their inhibitory effect on tumor-bearing mice models.

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Land application of wastes generated from concentrated animal feeding operations may result in accumulation of tetracyclines (TCs) and metals in agricultural soils. Adsorption of TCs and metals on soil minerals strongly affects their mobility. This study was conducted to evaluate the interaction between tetracycline (TC) and Cu(ll) with regard to their adsorption and cosorption on montmorillonite as affected by solution pH.

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Cosorption of metals with herbicides on minerals affects their mobility and their environmental effect. Batch experiments were conducted to evaluate the interaction between Zn and glyphosate [N-(phosphonomethyl)glycine (GPS; H3L)] with regard to the effect of GPS on Zn adsorption on goethite. The herbicide GPS markedly affected Zn adsorption on goethite when they coexisted in a goethite suspension.

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Recombinant human endostatin (rhEndostatin) has been shown to inhibit tumor growth, but the variable antitumor activity of different rhEndostatin preparations has necessitated the development of an accurate, reproducible in vivo bioassay for evaluating the rhEndostatin activity. To assess the in vivo antitumor efficacy of rhEndostatin, H22 tumor-bearing mice received three doses of rhEndostatin and the potency of rhEndostatin preparations in inhibiting tumor growth was determined by ED(50)-potency assay and validated by dose-response parallel-line assay. There was a consistent and highly reproducible linear regression relationship between rhEndostatin dosage and tumor growth inhibition rate.

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In order to establish the methods of high-performance liquid chromatography (HPLC) for determining the purity of recombinant human endostatin (rhEndostatin) and in vitro or in vivo activity of rhEndostatin, two columns were firstly used in HPLC analysis for determining the purity of rhEndostatin, including Waters Symmetry 300C4 (4.6 mm x 250 mm, 5 microm) and the Superdex75 HR 10/30. Cell lines, bovine capillary endothelial cells (BCEs) or human umbilical vein endothelial cells (HUVECs) expression human vascular endothelial growth factor (hVEGF) were used in method MTT or LDH as substrate, respectively.

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