Identification of the promoter region and the 5'-untranslated exons of the human voltage-gated sodium channel Nav1.1 gene (SCN1A) and enhancement of gene expression by the 5'-untranslated exons.

Voltage-gated sodium channels play critical roles in the excitability of the brain. A decreased level of Na(v)1.1 has been identified as the cause of severe myoclonic epilepsy in infancy.

[Changes of potassium channels Kv4.2, Kv4.3 and Kv channel interacting protein 1 in amygdala kindling epilepsy: experiment with rats].

Objective: To investigate the changes of the potassium channels voltage gated potassium channel (Kv) 4.2, Kv4.3, and Kv interacting protein 1 (KChIP1) during the process of amygdala kindling epilepsy and possible role thereof.