Publications by authors named "Hao-Yun Chen"

Article Synopsis
  • The study compares narrow and wide gastric conduit methods for esophageal reconstruction in 493 esophageal cancer patients to evaluate complications like anastomotic leakage and strictures.
  • Results showed that patients with narrow gastric conduits had lower rates of anastomotic leakage, shorter hospital stays, and less need for post-operation dilatation compared to those with wide conduits.
  • The findings suggest that narrow gastric conduits are a viable alternative to wide ones, with outcomes indicating similar effectiveness in preventing complications post-surgery.
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Background: Esophageal cancer has extreme worldwide demographic and histologic variations in occurrence; thus, understanding the pathogenesis of esophageal cancer must be region- or country-based. We examined the incidence and tumor stage at diagnosis of esophageal cancer in relation to patients' socioeconomic status (SES) in Taiwan.

Method: This retrospective cohort study used data from Taiwan's National Health Insurance Research Database and Taiwan Cancer Registry collected between January 2008 and December 2014.

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Cancer cachexia (CC), characterized by body weight loss and sarcopenia, contributes to over 20% of all cancer-related death. Approximately 80% of pancreatic cancer (PC) patients develop CC during disease progression. Pro-inflammatory cytokines, including interleukin (IL)-1β, IL-6, IL-8, and tumor necrosis factor (TNF)-α, have been correlated with CC; however, its prognostic significance remains unclear.

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A variety of approaches have been proposed for overcoming the unpleasant side effects associated with antibiotics treatment of () infections. Research has shown that epigallocatechin-3-gallate (EGCG), a major ingredient in green tea, has antibacterial activity for antiurease activity against . Oral EGCG is not good because of its digestive instability and the fact that it often cannot reach the targeted site of antibacterial activity.

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