Publications by authors named "Hao-Yu Feng"

Article Synopsis
  • This study looked at 139 patients with a neck problem called degenerative cervical spondylotic myelopathy (DCM) who had surgery to fix it.
  • The patients were divided into three groups based on the severity of their condition: mild, moderate, and severe, and their pain and movement were measured before and after surgery.
  • Results showed that all groups had better scores for pain and movement after surgery, with differences between the groups indicating that the more complex the condition, the greater the improvement needed.
View Article and Find Full Text PDF
Article Synopsis
  • This study compared unilateral versus bilateral pedicle screw fixation and fusion in treating atlantoaxial fracture-dislocation in 28 patients over several years.
  • Results showed both methods significantly improved neck pain and neurological function, with proper stability and implant placement in follow-up imaging.
  • Unilateral fixation can be a viable option, particularly for cases with anatomical difficulties or trauma, offering a successful alternative for restoring stability.
View Article and Find Full Text PDF

In order to analyze and evaluate the stability of lumbar spine and the risk of cage subsidence after different minimally invasive fusion operations, two finite element models Percutaneous endoscopic posterior lumbar interbody fusion (PE-PLIF) and minimally invasive transforaminal lumbar interbody Fusion (MIS-TLIF) were established. The results showed that compared with MIS-TLIF, PE-PLIF had better segmental stability, lower pedicle screw rod system stress, and lower risk of cage subsidence. The results suggest that the cage with appropriate height should be selected to ensure the segmental stability and avoid the risk of the subsidence caused by the cage with large height.

View Article and Find Full Text PDF
Article Synopsis
  • * The discovery of autoantibodies against phospholipase A receptor (PLAR) and other antigens has provided new insights into MN's pathology and led to more accurate diagnosis methods, allowing for routine detection of anti-PLAR antibodies.
  • * The review highlights new diagnostic biomarkers like PLAR and THSD7A, as well as potential therapies including traditional Chinese medicines, while addressing ongoing questions and future challenges in treating MN effectively.
View Article and Find Full Text PDF

Background: Endoscopic lumbar interbody fusion is a new technology that is mostly used for single-segment and unilateral lumbar spine surgery. The purpose of this study is to introduce percutaneous endoscopic posterior lumbar interbody fusion (PE-PLIF) with unilateral laminotomy for bilateral decompression (ULBD) for lumbar spondylolisthesis and evaluate the efficacy by comparing it with open posterior lumbar interbody fusion (PLIF).

Methods: Twenty-eight patients were enrolled in PE-PLIF with the ULBD group and the open PLIF group.

View Article and Find Full Text PDF

Background: Endoscopic lumbar interbody fusion has become an emerging technique. Some researchers have reported the technique of percutaneous endoscopic transforaminal lumbar interbody fusion. We propose percutaneous endoscopic posterior lumbar interbody fusion (PE-PLIF) as an alternative approach.

View Article and Find Full Text PDF

Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that induces the expression of a broad range of downstream genes such as cytochromes P450 enzymes and cyclooxygenase-2. Recent research focuses are shifting from AhR activation induced by xenobiotics to its response patterns to physiological ligands that expand our understanding of how endogenous metabolites as ligands to modulate AhR signaling pathway under homeostasis and pathological conditions. With increasing interest in AhR and its endogenous ligands, it would seem advisable to summarize a variety of endogenous ligands especially host/gut microbiota-derived tryptophan metabolites.

View Article and Find Full Text PDF