Publications by authors named "Hao-Yang Ma"
As a selective estrogen receptor modulator (SERM), raloxifene is used in healthy postmenopausal women to prevent bone loss and reduce fractures. However, the benefit of raloxifene is uncertain in the treatment of osteoporosis among patients with end-stage renal disease (ESRD) or those who require maintenance dialysis. We assessed the safety and efficacy of raloxifene in this particular population.
View Article and Find Full Text PDFAcute kidney injury (AKI) and chronic kidney disease (CKD) are posing great threats to global health within this century. Studies have suggested that estrogen and estrogen receptors (ERs) play important roles in many physiological processes in the kidney. For instance, they are crucial in maintaining mitochondrial homeostasis and modulating endothelin-1 (ET-1) system in the kidney.
View Article and Find Full Text PDFArticle Synopsis
- This meta-analysis investigates the potential of TWEAK as a diagnostic biomarker for lupus nephritis (LN), showing that it is elevated in patients with the condition.
- The analysis included data from nine studies and found that TWEAK has a sensitivity of 0.69 and specificity of 0.77 for identifying active LN.
- The study suggests TWEAK could be a promising biomarker, but more research is needed to confirm its diagnostic effectiveness and determine specific cutoff values for active LN.