Publications by authors named "Hao-Wen Zhuang"
Article Synopsis
- XYT (Xinyang Tablet) has been clinically used for heart failure for over two decades, but its molecular mechanisms are not well defined.
- The study explored XYT's protective effects on heart function using both live mouse models and cardiomyocyte cell cultures under stress, particularly looking at mitochondrial health.
- Results indicated that XYT significantly improved cardiac function and structure in mice with pressure overload by reducing mitochondrial damage and enhancing protein responses related to mitochondrial health.
Background: Osteosarcomas (OS) is a kind of malignant bone tumor which occurs primarily in children and adolescents, and the clinical therapeutics remain disappointing. As a new programmed cell death, ferroptosis is characterized by iron dependent and intracellular oxidative accumulation, which provides a potential alternative intervene for the OS treatment. Baicalin, a major bioactive flavone derived from traditional Chinese medicine Scutellaria baicalensis, has been proved to have anti-tumor properties in OS.
View Article and Find Full Text PDFBACKGROUND Renal dysfunction is a leading cause of death in patients with acute pancreatitis (AP) and often occurs later than respiratory complications. Whether respiratory complications can predict renal impairment remains unclear. The aim of this study was to investigate the association between pleural effusion and renal dysfunction in AP.
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