In recent years, there has been an increase in the scientific production of youth soccer. However, a panoramic map of research on this subject does not exist. The aim of this study was to identify global research trends in youth soccer over time, among the main levels of analysis: sources, authors, documents, and keywords.
View Article and Find Full Text PDFDepression is a common psychiatric comorbidity in patients with epilepsy, especially those with temporal lobe epilepsy (TLE). The aim of this study was to assess changes in high mobility group box protein 1 (HMGB1) expression in epileptic patients with and without comorbid depression. Sixty patients with drug-resistant TLE who underwent anterior temporal lobectomy were enrolled.
View Article and Find Full Text PDFAsymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase and plays a significant role in the pathogenesis of arteriovenous fistula (AVF) dysfunction. The aim of this study is to evaluate the effect of far-infrared (FIR) therapy on the maturation and patency of newly-created AVFs in patients with advanced diabetic kidney disease (DKD) as well as the concurrent change in plasma ADMA. The study enrolled 144 participants with advanced DKD where 101 patients were randomly allocated to the FIR therapy group (N = 50) and control group (N = 51).
View Article and Find Full Text PDFThree new aristololactam derivatives, aristololactam W-Y (1-3), and three known compounds (4-6) were isolated from the fruits of Aristolochia contorta Bunge. Compounds 1 and 2 represent the first example of an N-CHOCH aristololactam derivative from natural products. Their structures were elucidated by 1D/2D NMR and HRESIMS spectra.
View Article and Find Full Text PDFCyclization of the ether enyne 1 catalyzed by [Ru]NCCH3(+) ([Ru] = Cp(PPh3)2Ru) in CHCl3 generates a diastereomeric mixture of the substituted tetrahydropyran 11. Presumably, formation of an allenylidene complex is followed by a cyclization by nucleophilic addition of the olefinic group to Cγ of the ligand giving a boat-like six-membered ring. The diastereoselectivity is controlled by the 1,3-diaxial interaction.
View Article and Find Full Text PDFConsecutive cyclization reactions of phenyl propargyl alcohols 1 and 2 are catalyzed by [Ru]NCCH(3)(+) ([Ru] = Cp(PPh(3))(2)Ru) in cosolvent CHCl(3)/MeOH at 60 °C, to afford the fused cyclic compounds 11a (R = Me) and 10a (R = Me), respectively.
View Article and Find Full Text PDFThe reactions of [Cp(PPh(3))(2) RuCl] (Cp=cyclopentadienyl) with phenyl propargylic alcohol 1a, with a 3-thiophene group, are explored. The carbene complex 2a, obtained exclusively from this reaction at low temperature, contains the naphthothiophene group, which is formed through a new cyclization process between the thiophene group and the inner carbon of the triple bond. Details of this process have been revealed by conducting the reaction at room temperature, affording the allenylidene complex 3a as a side product.
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