Effects of 7-methylxanthine on form-deprivation myopia in pigmented rabbits.

Aim: To determine the effect of 7-methylxanthine (7-MX) on the posterior sclera of form-deprivation myopia (FDM) in pigmented rabbits.

Methods: Sixteen pigmented rabbits were monocularly deprived (MD) by suturing the right eyelids after natural eye opening (ten-day old) for a period of 30 days. Two groups of pigmented rabbits were fed either 7-MX (30 mg per kg body weight; n=8) or vehicle control (saline equal volume with 7-MX; n=8).

[Effects of experimentally induced hyperopic optical defocus on refractive status of adolescent monkeys].

Objective: To determine if chronic optical defocus alters refractive development in monkeys at ages corresponding to the typically developed age of myopia in human children.

Methods: A hyperopic anisometropia was produced in 7 adolescent rhesus monkeys by photorefractive keratectomy (PRK). The laser procedures were performed when the monkeys were 2.

[Comparison of retinal morphology and ultrastructure in defocus-induced myopia and form-deprivation myopia in rhesus monkeys].

Objective: To investigate the changes of retinal ultrastructure of defocus-induced myopia and form-deprivation myopia in infant rhesus monkeys.

Methods: A -3.00 D spectacle lens (n = 9) or diffuser lens (n = 6) was worn over one eye and a zero-powered lens over the fellow eye in 15 healthy rhesus monkeys ranging in age from 1 to 1.

[The study of photorefractive keratectomy induced defocus on emmetropization in infant monkeys].

Objective: To investigate the effect of photorefractive keratectomy (PRK) induced defocus on emmetropization in infant rhesus monkeys and to determine the role of visual feedback on emmetropization.

Methods: PRK was performed in 8 healthy rhesus monkeys age ranging from 2 to 3 months. Either 3.