The Bioaccumulation, Fractionation and Health Risk of Rare Earth Elements in Wild Fish of Guangzhou City, China.

In this study, the total content of REEs ranged from 1.32 to 67.74 μg/kg, with a predominant presence of light REEs.

Effect of CYP3A5*3 genotype on exposure and efficacy of quetiapine: A retrospective, cohort study.

Background: The involvement of cytochrome P450 3A5 (CYP3A5) in the metabolism of quetiapine has been proposed, though conclusive evidence is lacking. This study aimed to quantitatively assess the impact of CYP3A5 genetic variability on quetiapine exposure in a Chinese patient population.

Methods: Patient data were retrospectively collected from the database of the Mental Health Centre at the First Hospital of Hebei Medical University, covering the period from September 1, 2019, to July 1, 2023.

The variations of heavy metals sources varied their aggregated concentration and health risk in sediments of karst rivers - A case study in Liujiang River Basin, Southwest China.

The sources and health risk variation of heavy metals (HMs) in sediments of Liujiang River Basin were investigated seasonally to clear the control of HMs contamination in karst rivers. The results revealed the exogenous input of HMs should be more prominent in wet season, due to the higher concentration and EF values. PMF identified HMs were mainly from natural, mining and industrial sources.

Predicting quetiapine dose in patients with depression using machine learning techniques based on real-world evidence.

Background: Being one of the most widespread, pervasive, and troublesome illnesses in the world, depression causes dysfunction in various spheres of individual and social life. Regrettably, despite obtaining evidence-based antidepressant medication, up to 70% of people are going to continue to experience troublesome symptoms. Quetiapine, as one of the most commonly prescribed antipsychotic medication worldwide, has been reported as an effective augmentation strategy to antidepressants.

The distribution, sources and health risk of polycyclic aromatic hydrocarbons (PAHs) in sediments of Liujiang River Basin: A field study in typical karstic river.

The accumulation of PAHs in sediments of Liujiang River Basin were investigated to disclose the sources, input processes and toxicity risk of PAHs in a typical karstic river. The results revealed the concentrations of ∑PAHs are ranging from 111.97 to 593.

The Size Screening Could Greatly Degrade the Health Risk of Fish Consuming Associated to Metals Pollution-An Investigation of Angling Fish in Guangzhou, China.

Fish size can heavily impact the bioaccumulation of metals, but it was rarely applied to screen out the fish with low health risk for consuming. Given the widespread metals contamination of angling fish, the angling fish collected from Guangzhou, China, were taken as an example in this study. The screening length and weight were detailed in accordance with the investigation of metals contamination among angling fish.

The Influence of the Reduction in Clay Sediments in the Level of Metals Bioavailability-An Investigation in Liujiang River Basin after Wet Season.

The seasonal elevation of metals' bioavailability can aggravate the threat of metal contamination in the aquatic environment. Nevertheless, their regulations have rarely been studied, particularly the connections between metals' transformation and environmental variations. Therefore, the catchment area of Liujiang River was taken as an example in this study, their seasonal variations in metals' bioavailability in sediments, especially during the wet season, was investigated to recover the processes associated with metals' speciations and multiple environmental factors.

The Accumulation and Transformation of Heavy Metals in Sediments of Liujiang River Basin in Southern China and Their Threatening on Water Security.

Heavy metal (HM) pollution in sediments is tightly related to the security of water quality in rivers, but the accumulation and conversion of HMs are poorly researched, so that a field study was conducted as an example in the Liujiang River Basin. Seven HMs were analyzed to determine between the overlying water and sediments. Moreover, the regulation of HMs speciation and environmental factors in their accumulation and conversion were identified.

The Bioaccumulation and Health Risk Assessment of Metals among Two Most Consumed Species of Angling Fish ( and ) in Liuzhou (China): Winter Should Be Treated as a Suitable Season for Fish Angling.

Wild fish caught by anglers were validated to be commonly polluted by metals, but their contamination status could be varied with changing seasons. To determine the seasonal variation in metal pollution and health risks in these fish, this study took Liuzhou City as an example to investigate the concentrations of eight metals in two dominant angling fishes ( and ) collected, respectively, in winter and summer. The obtained results suggested the mean concentrations of metals in fish are overall lower in winter.

The Variation of Heavy Metals Bioavailability in Sediments of Liujiang River Basin, SW China Associated to Their Speciations and Environmental Fluctuations, a Field Study in Typical Karstic River.

The bioavailability of heavy metals (HMs) in sediments is closely related to the security of the aquatic environment, but their impacts are poorly researched, particularly in karstic rivers. Therefore, Liujiang River Basin was taken as an example in this study. Seven HMs were analyzed to determine the bioavailability and speciations of HMs in sediments.

Effects of heavy metals speciations in sediments on their bioaccumulation in wild fish in rivers in Liuzhou-A typical karst catchment in southwest China.

Although fish are widely confirmed to be susceptible to heavy metals (HMs) contamination in sediments, this bioconversion haven't been detailed. This is especially the case in karst areas, where HMs are less stably retained in the sediments and are more bioavailable. Therefore, we surveyed representative karst rivers in Liuzhou, China, in order to study the relationship between the speciations of seven HMs in the sediments with their bioaccumulation in wild fish.

Health Risk Assessment of Metals (Cu, Pb, Zn, Cr, Cd, As, Hg, Se) in Angling Fish with Different Lengths Collected from Liuzhou, China.

Wild fish caught by anglers (WFAs) were confirmed to be usually contaminated with metals, and the contamination status is radically affected by the growth and length of the fish. To determine the contamination levels of metals and health risks in WFAs with different length ranges of fish, this study ascertained the concentration of eight metals, including Cu, Pb, Zn, Cr, Cd, As, Hg and Se, in 171 wild fishes collected from the watershed of Liujiang River. The assessment of metal pollution and health risks from the consumption of these fishes with seven length ranges were accomplished.

Analysis and health risk assessment of toxic and essential elements of the wild fish caught by anglers in Liuzhou as a large industrial city of China.

Most wild fish caught by anglers (WFAs) are likely to be contaminated by toxic metals, particularly the fish collected from the waterways in urban and suburban areas; hence, the determination of health risk caused by WFAs consumption associated with toxic metals is vital. Therefore, Liuzhou, one of the largest industrial cities in China, was considered as an example city in this study. Eight toxic elements were analysed to uncover the pollution status and consumption safety of WFAs.

Correction to: Spatial distribution of heavy metals and their potential sources in the soil of Yellow River Delta: a traditional oil field in China.

In the original publication of the article, the sixth author name "Zhouqing Xie" has been misspelt. The correct name is given in this correction. The original version of this article was revised.

Spatial distribution of heavy metals and their potential sources in the soil of Yellow River Delta: a traditional oil field in China.

In this study, soil samples were collected from different layers throughout the whole Yellow River Delta (YERD), in north China. The total concentration of arsenic (As), cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), lead (Pb) and zinc (Zn) was determined to demonstrate their spatial distribution and pollution status in different layers of soils throughout the whole YERD. The obtained results suggested a relatively low contamination of heavy metals as observed through the evaluation of CF and RI.