Global food loss and waste continues to increase despite efforts to reduce it. Food waste causes a disproportionally large carbon footprint and resource burdens, which require urgent action to transition away from a disposal-dominated linear system to a circular bioeconomy of recovery and reuse of valuable resources. Here, using data from field-based studies conducted under diverse conditions worldwide, we found collective evidence that composting, anaerobic digestion and repurposing food waste to animal feed (re-feed) result in emission reductions of about 1 tCOe t food waste recycled compared with landfill disposal.
View Article and Find Full Text PDFUnderstanding DOM composition is essential for investigating the biogeochemical carbon cycle and related elements. However, methods for assigning molecular formulas (MF) in high-resolution mass spectrometry remain poorly defined, which often resulting in the misidentification of DOM components. In this study, we established a metrics evaluation framework for assessing the assignment results of each method based on similarity, accuracy and correctness.
View Article and Find Full Text PDFTo identify genomic regions subject to positive selection that might contain genes involved in high-altitude adaptation (HAA), we performed a genome-wide scan by whole-genome sequencing of Tibetan highlanders and Han lowlanders. We revealed a collection of candidate genes located in 30 genomic loci under positive selection. Among them, MCUR1 at 6p23 was a novel pronounced candidate.
View Article and Find Full Text PDFIncreased catecholamine (CA) secretion from the adrenal medulla has been observed in patients with Metabolic Syndrome (MetS) and in animal models. Neuroendocrine adrenal medulla chromaffin cells (AMCCs) release catecholamines in response to Ca influx through calcium channels. This study investigates the role of TRPC channels in mediating calcium influx in AMCCs under MetS conditions.
View Article and Find Full Text PDFBackground: Parturition is similar to an inflammatory response in which resident and infiltrating immune cells release cytokines and chemokines into the maternal-fetal interface, promoting expulsion of the fetus from the mother. The untimely activation of these inflammatory pathways can result in preterm labor. The maternal-fetal interface is composed mainly of decidual tissue and placental villous space.
View Article and Find Full Text PDFThyroid hormone and its receptors (TRs) are crucial for late-stage cochlear development and the maintenance of endocochlear potential (EP), yet the mechanisms underlying EP reduction in their absence remain unclear. Cochlear outer sulcus root cells undergo significant morphological changes during late-stage development and are thought to play a role in maintaining endolymph homeostasis and EP. Nevertheless, it remains unknown whether thyroid hormone and TRs are essential for root cell differentiation and function.
View Article and Find Full Text PDFPassive thermal management saves energy using natural processes but struggles with precise temperature control in variable environments. This study designs and synthesizes temperature-programmable hydrogels (TPH) based on a bilayer polyvinyl alcohol network with tunable passive heating capacity. The TPH features an upper layer with adjustable transmittance (6.
View Article and Find Full Text PDFBackground And Purpose: The intracerebral hemorrhage (ICH) score was created as a tool improve communication and consistency among providers, and authors initially cautioned against its use as a predictor of outcomes. We aimed to investigate the association of ICH score with mortality and withdrawal of life-sustaining treatment (WLST).
Methods: Patients with a diagnosis of ICH were identified using data from Florida Stroke Registry (FSR) hospitals participating in the American Heart Association (AHA) Get with the Guidelines-Stroke (GWTG-S) from 2013-2022.
Background And Objectives: Although ischemic stroke (IS) in young patients (aged 18-55) is believed to have different etiologies than in older patients, a rise in vascular risk factors (VRFs) among young adults may translate to an IS risk profile similar to the older population. We aimed to examine the prevalence of VRFs and temporal trends in VRF burden among young patients presenting with IS.
Methods: Data were prospectively collected by Get With the Guidelines-Stroke hospitals participating in the Florida Stroke Registry between January 2014 and December 2022.
Widespread uranium mining resulted in large amounts of radioactive wastes. While impoundment has been commonly used to store U-laden wastes, information has been lacking on the secondary contamination potential. We conducted a field-scale study at a prototype uranium mine tailings impoundment site in China to understand the abnormally high concentrations (0.
View Article and Find Full Text PDFis a very rare pathogen that causes intracranial infection. It is commonly found in immunocompromised patients and is resistant to multiple antibiotics. In this case report, we present a case of human central nervous system infection caused by , which was initially misdiagnosed as demyelinating disease due to the specific imaging findings.
View Article and Find Full Text PDFBackground And Purpose: Endovascular thrombectomy outcomes are impacted by changes in stroke systems of care. During the pandemic, SARS-CoV2 positive status had major implications on hospital arrival and treatment models of non-COVID related hospital admissions. Using the Florida Stroke Registry, we compared the rates of in-hospital death and discharge outcomes of patients treated with endovascular thrombectomy who tested positive for SARS-CoV2 infection during their hospitalization.
View Article and Find Full Text PDFTo better understand the growth adaptability of various maize varieties to the climate of the Alar region in Southern Xinjiang Province, an experiment was conducted using seven distinct maize varieties as test materials. A one-way randomized block design was applied to both experimental groups. In 2021 and 2022, a total of 19 indicators were observed for comparative analysis, including antioxidant enzyme activities and agronomic traits.
View Article and Find Full Text PDFBackground: Resource allocation for stroke care was impacted worldwide by the Coronavirus 2019 (COVID19) pandemic. Regionally, worsened stroke outcomes varied, however comparative year-over-year in-hospital performance metrics from the pandemic are unreported. Therefore, within the large Florida Stroke Registry (FSR), we assessed the pandemic's effects upon the American Heart Association (AHA) Get With The Guidelines (GWTG) ischemic stroke metrics and the meta-metric, Defect-Free Care (DFC).
View Article and Find Full Text PDFGenomics Proteomics Bioinformatics
January 2025
Aeromonas veronii has emerged as a significant pathogen that impacts both fish and mammals. Recently, an infectious disease characterized by multiple ulcers on the body surface with a high mortality rate occurred in Channa argus cultured in Jiangsu Province, China. A Gram-negative bacterial strain (Aer12) was isolated from the body surface of the diseased fish and identified as A.
View Article and Find Full Text PDFThis study identifies the association between patient perception of discharge education/resources and adequate transitions of care (ATOC) (i.e., patient achievement of at least 75% of recommended positive behaviors and activities within 30 days post-stroke hospitalization).
View Article and Find Full Text PDFGlycerol kinase (GK) participates in triglyceride (TG) synthesis by catalyzing glycerol metabolism. Whether GK contributes to nonalcoholic fatty liver (NAFL) is unclear. The expression of hepatic Gk is found to be increased in diet-induced and genetic mouse models of NAFL and is positively associated with hepatic SREBP-1c expression and TG levels.
View Article and Find Full Text PDFContinuous exposure to environmental hypoxia (11% O) has been shown to markedly slow the progressive degeneration of retinal ganglion cells (RGCs) in a mouse model of mitochondrial optic neuropathy with RGC-specific deletion of the key mitochondrial complex I accessory subunit ndufs4. As a first step toward identifying the therapeutic mechanism of hypoxia in this model, we conducted a series of experiments to investigate the role of the hypoxia-inducible factor (HIF) regulatory pathway in RGC neuroprotection. Vglut2-Cre; ndufs4 mice were crossed with strains bearing floxed alleles of the negative HIF regulatory vhl or of the two major HIF α-subunit isoforms, Hif1α and Hif2α.
View Article and Find Full Text PDFAcylcarnitine (ACar) is a novel fuel source for activating thermogenesis in brown adipose tissue (BAT). However, whether ACar metabolism underlies BAT thermogenesis decline with aging remain unclear. Here, the L-carnitine-treated young and aging mice were used to investigate the effects of activation of ACar metabolism on BAT thermogenesis during aging.
View Article and Find Full Text PDFThe hypothalamus is an important component of the hypothalamic-pituitary-adrenal axis and an important brain region of the limbic system. Twenty-four first depressive episode(FDE) patients and 25 healthy controls were recruited for this study. The hypothalamus was used as a seed to observe the characteristics of resting state and dynamic functional connectivity (FC) changes in FDE patients, and further observed the correlation between the different brain regions and clinical symptoms.
View Article and Find Full Text PDFStem cell derived small extracellular vesicles (sEVs) have emerged as promising nanomaterials for the repair of bone defects. However, low retention of sEVs affects their therapeutic effects. Clinically used natural substitute inorganic bovine bone mineral (Bio-Oss) bone powder lacks high compactibility and efficient osteo-inductivity that limit its clinical application in repairing large bone defects.
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