Glissando-Net: Deep Single View Category Level Pose Estimation and 3D Reconstruction.

We present a deep learning model, dubbed Glissando-Net, to simultaneously estimate the pose and reconstruct the 3D shape of objects at the category level from a single RGB image. Previous works predominantly focused on either estimating poses (often at the instance level), or reconstructing shapes, but not both. Glissando-Net is composed of two auto-encoders that are jointly trained, one for RGB images and the other for point clouds.

A novel navigation assistant method for substation inspection robot based on multisensory information fusion.

Introduction: Due to the complex environment of the substation, the inspection work of the substation becomes time-consuming and laborious. As a result, the substation inspection robot has gradually become a hot research point.

Objectives: At present, the mainstream intelligent inspection robots for substations use high-precision LiDAR sensors for navigation, which has high navigation accuracy but cannot identify the types of obstacles and the road contour boundary, seriously affecting the inspection performance and efficiency.

Boosting the Reaction Rate of Blocky Aluminum-Water via Ultrasound-Based Surface Engineering in Room-Temperature Liquid Metal Solvent.

Hydrogen gas holds immense promise as a clean fuel source, yet its widespread adoption faces significant challenges in storage and transportation due to its gaseous and highly flammable nature. An increasingly attractive approach to overcoming these limitations involves reacting aluminum (Al) blocks with water to produce hydrogen, providing an alternative distribution mechanism in which Al blocks can be used as "hydrogen storage" for on-demand production at any location. However, current methods suffer poor hydrogen production rates and yields, primarily influenced by the limited contact area between Al and the catalyst, such as Ga-based room-temperature liquid metal.

Life's essential 8 and mortality in US adults with metabolic dysfunction-associated steatotic liver disease.

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is linked to increased all-cause mortality due to metabolic dysfunctions like obesity, diabetes, and cardiovascular diseases. This study examines the association between Life's Essential 8 (LE8) scores and both all-cause and cardiovascular disease (CVD) mortality in MASLD participants.

Methods: Data from 5,916 MASLD participants in the NHANES (2005-2018) were analyzed.

Latent profile of personality traits for American older adults and its transition during the COVID-19 pandemic.

Background: The impact of COVID-19 on older adults' personality development is essential for emergency management but under-researched. This study seeks to explore the personality profiles of older adults living in the United States and how these profiles transitioned during the pandemic.

Methods: Longitudinal data were collected from 3,550 adults aged 60 and older who participated in both the 2016 and 2020 waves of the Health and Retirement Survey (61.

Application of hydrophobic catalyst in formaldehyde-ethylene condensation reaction.

Using hydrophobic aerogel (AGL) as the carrier, the catalyst supported p-toluene sulfonic acid (p-TSA) is synthesized, and the impact of the hydrophobicity of the catalyst on the formaldehyde-ethylene condensation reaction is investigated. Water contact angle, XRD, N2 adsorption/desorption, IR, and thermogravimetric analysis are used to characterize the catalyst. The outcomes demonstrate the ability of p-TSA to be loaded onto the carrier and the strong hydrophobicity of the catalyst when using AGL as the carrier.

Sonication-Assisted Electrochemical Synthesis of Silver Nanoparticles.

In this work, we propose a method for synthesizing silver nanoparticles (Ag NPs) utilizing a sonication-assisted electrochemical approach with a common ultrasonic cleaner. Silver nitrate is employed as the precursor and polyvinylpyrrolidone functions as the ligand. The incorporation of sonication is identified as crucial for achieving several benefits such as enhanced mass transfer, improved dispersion of reactants, and the prevention of electrode fouling.

Risk factors and prognostic factors associated with retinal detachment and visual outcomes in acute retinal necrosis.

Objective: To investigate the risk factors and prognostic factors that affect the long-term clinical outcomes of acute retinal necrosis (ARN).

Methods: A retrospective study of patients with ARN who underwent treatment and completed follow-up in our ophthalmology department from 2011 to 2021 was conducted. The incidence and risk factors of retinal detachment (RD) and prognostic factors affecting long-term clinical outcomes, such as late-onset RD and final vision loss (< 20/200), were analyzed.

Synthesis of Polycyclic Aromatic Compounds by Electrocyclization-Dehydrogenation of Diradicaloids.

Herein, we present a novel and efficient method for the synthesis of two new polycyclic aromatic hydrocarbons, and , through the electrocyclization-dehydrogenation of diradicaloids. The proposed oxidative electrocyclization via intermediate diradicaloids is monitored by electron paramagnetic resonance and ultraviolet-visible spectroscopy. Interestingly, exhibits chirality because of its inherent helical skeleton, and features long-wavelength absorption and near-infrared emission properties due to its extended π-conjugation.

Nanomedicines Targeting Ferroptosis to Treat Stress-Related Diseases.

Ferroptosis, a unique form of regulated cell death driven by iron-dependent lethal lipid peroxidation, is implicated in various stress-related diseases like neurodegeneration, vasculopathy, and metabolic disturbance. Stress-related diseases encompass widespread medical disorders that are influenced or exacerbated by stress. These stressors can manifest in various organ or tissue systems and have significant implications for human overall health.

Comparative morphology of the cruciate ligaments: A radiological study.

Background: The anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) are important structures to maintain knee stability. The present study aimed to further enrich understandings of the morphology of the cruciate ligaments and explore the relationship between the diameter of ACL and PCL.

Method: This study collected valid MRI samples of 50 male and 50 female normal right knee joints and measured the diameter of each point of the ACL and PCL through the 3D Slicer.

Real-time coloration control of gallium-based strips through cold rolling.

Cold rolling has been used as a real-time surface oxidation control method to create colored strips on flexible substrates. By controlling the extrusion rate in real time, a variety of colored strips have been fabricated on Ga-based liquid metal (LM) strips. X-ray photoelectron spectroscopy (XPS) analysis shows that the surfaces of the colored strips, which were obtained through extrusion rate control of LM-Al, consist primarily of metal oxide composites, including GaO, GaO, AlO, SnO, and InO.

Genomic Insights into the Role of TOP Gene Family in Soft-Tissue Sarcomas: Implications for Prognosis and Therapy.

This study focuses on the role of topoisomerases (TOPs) in sarcomas (SARCs), highlighting TOPs' influence on sarcoma prognosis through mRNA expression, genetic mutations, immune infiltration, and DNA methylation analysis using transcriptase sequencing and other techniques. The findings indicate that TOP gene mutations correlate with increased inflammation, immune cell infiltration, DNA repair abnormalities, and mitochondrial fusion genes alterations, all of which negatively affect sarcoma prognosis. Abnormal TOP expression may independently affect sarcoma patients' survival.

Applications of Hydrogels in Osteoarthritis Treatment.

This review critically evaluates advancements in multifunctional hydrogels, particularly focusing on their applications in osteoarthritis (OA) therapy. As research evolves from traditional natural materials, there is a significant shift towards synthetic and composite hydrogels, known for their superior mechanical properties and enhanced biodegradability. This review spotlights novel applications such as injectable hydrogels, microneedle technology, and responsive hydrogels, which have revolutionized OA treatment through targeted and efficient therapeutic delivery.

Genkwanin alleviates intervertebral disc degeneration via regulating ITGA2/PI3K/AKT pathway and inhibiting apoptosis and senescence.

Intervertebral disc degeneration (IVDD) is a progressive degenerative disease influenced by various factors. Genkwanin, a known anti-inflammatory flavonoid, has not been explored for its potential in IVDD management. This study aims to investigate the effects and mechanisms of genkwanin on IVDD.

Chromosome-level genome assembly and characterization of the Calophaca sinica genome.

Calophaca sinica is a rare plant endemic to northern China which belongs to the Fabaceae family and possesses rich nutritional value. To support the preservation of the genetic resources of this plant, we have successfully generated a high-quality genome of C. sinica (1.

A novel ratiometric fluorescent probe with high selectivity for lysosomal nitric oxide imaging.

Nitric oxide (NO) plays critical roles in both physiology and pathology, serving as a significant signaling molecule. Recent investigations have uncovered the pivotal role of lysosome as a critical organelle where intracellular NO exists and takes function. In this study, we developed a novel ratiometric fluorescent probe called XL-NO and modified it with a morpholine unit, which followed the intramolecular charge transfer (ICT) mechanism.

Tumor-Derived Sarcopenia Factors Are Diverse in Different Tumor Types: A Pan-Cancer Analysis.

Cancer-associated muscle wasting is a widespread syndrome in people with cancer and is characterized by weight loss and muscle atrophy, leading to increased morbidity and mortality. However, the tumor-derived factors that affect the development of muscle wasting and the mechanism by which they act remain unknown. To address this knowledge gap, we aimed to delineate differences in tumor molecular characteristics (especially secretion characteristics) between patients with and without sarcopenia across 10 tumor types from The Cancer Genome Atlas (TCGA).

The Role of NCS1 in Immunotherapy and Prognosis of Human Cancer.

The Neural Calcium Sensor1 (NCS1) is a crucial protein that binds to Ca2 and is believed to play a role in regulating tumor invasion and cell proliferation. However, the role of NCS1 in immune infiltration and cancer prognosis is still unknown. Our study aimed to explore the expression profile, immune infiltration pattern, prognostic value, biological function, and potential compounds targeting NCS1 using public databases.

Performance of Metagenomic Next-Generation Sequencing of Cell-Free DNA From Vitreous and Aqueous Humor for Diagnoses of Intraocular Infections.

Background: Delayed diagnosis and improper therapy for intraocular infections usually result in poor prognosis. Due to limitations of conventional culture and polymerase chain reaction methods, most causative pathogens cannot be identified from vitreous humor (VH) or aqueous humor (AH) samples with limited volume.

Methods: Patients with suspected intraocular infections were enrolled from January 2019 to August 2021.

Autoimmune uveitis in Behçet's disease and Vogt-Koyanagi-Harada disease differ in tissue immune infiltration and T cell clonality.

Objectives: Non-infectious uveitis is often secondary to systemic autoimmune diseases, with Behçet's disease (BD) and Vogt-Koyanagi-Harada disease (VKHD) as the two most common causes. Uveitis in BD and VKHD can show similar clinical manifestations, but the underlying immunopathogenesis remains unclear.

Methods: To understand immune landscapes in inflammatory eye tissues, we performed single-cell RNA paired with T cell receptor (TCR) sequencing of immune cell infiltrates in aqueous humour from six patients with BD ( = 3) and VKHD ( = 3) uveitis patients.

Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF‑κB and MAPK signalling transduction through integrin αVβ3.

Osteoarthritis (OA) is a chronic progressive articular illness which commonly affects older‑aged adults, presenting with cartilage inflammation and degradation. Rutaecarpine (RUT) has been shown to exert promising anti‑inflammatory effects; however, the efficacy of RUT in the treatment of OA is debatable. The present study investigated the potential of RUT in alleviating OA in a mouse model.

Functionalization of Pentacene: A Facile and Versatile Approach to Contorted Polycyclic Aromatic Hydrocarbons.

In this work, a facile and versatile strategy for the synthesis of contorted polycyclic aromatic hydrocarbons (PAHs) starting from the functionalized pentacene was established. A series of novel PAHs 1-4 and their derivatives were synthesized through a simple two-step synthesis procedure involving an intramolecular reductive Friedel-Crafts cyclization of four newly synthesized pentacene aldehydes 5-8 as a key step. All the molecules were confirmed by single-crystal X-ray diffraction and their photophysical and electrochemical properties were studied in detail.

Asymptotic behavior of the basic reproduction number in an age-structured SIS epidemic patch model.

In this paper we consider an age-structured SIS epidemic patch model. We define the principal eigenvalue [Formula: see text], basic reproduction number [Formula: see text] and analyze the effects of the diffusion rate d on [Formula: see text] and [Formula: see text]. More precisely, we investigate their asymptotic behavior for small and large diffusion rates.