[Prokaryotic expression and purification of inorganic nitrogen transporters in wheat].

The nitrate transporter (NRT) and ammonium transporter (AMT) are crucial transmembrane proteins involved in the absorption, transport, and distribution of inorganic nitrogen in wheat. Obtaining NRT/AMT and preparing corresponding antibodies are conducive to probing into their tissue localization and comprehending the nitrogen utilization process in wheat. In this study, four genes (.

PET radiomics in lung cancer: advances and translational challenges.

Radiomics is an emerging field of medical imaging that aims at improving the accuracy of diagnosis, prognosis, treatment planning and monitoring non-invasively through the automated or semi-automated quantitative analysis of high-dimensional image features. Specifically in the field of nuclear medicine, radiomics utilizes imaging methods such as positron emission tomography (PET) and single photon emission computed tomography (SPECT) to evaluate biomarkers related to metabolism, blood flow, cellular activity and some biological pathways. Lung cancer ranks among the leading causes of cancer-related deaths globally, and radiomics analysis has shown great potential in guiding individualized therapy, assessing treatment response, and predicting clinical outcomes.

Clinical and biochemical characterization of asymptomatic carriers and symptomatic patients with hereditary transthyretin amyloidosis caused by TTR V30L mutation.

Background: Hereditary transthyretin amyloidosis (ATTR) is an autosomal dominant disease characterized by amyloid fibril deposition. The TTR c.148G > T mutation (V30L) in ATTR is rarely reported, and its biochemical properties are unknown.

Chlorogenic acid alleviate kidney fibrosis through regulating TLR4/NF-қB mediated oxidative stress and inflammation.

Ethnopharmacological Relevance: Chlorogenic acid (CGA), a phenolic acid produced by the interaction of Caffeic acid and Quinic acid, is considered to be the main active ingredient in many heat-clearing and detoxifying Chinese medicines, such as honeysuckle, Houttuynia, Artemisia annua, Gardenia, etc. CGA has anti-inflammatory, antioxidant, anticancer, antibacterial and other properties. However, the effect and process of CGA in kidney fibrosis remain unknown.

Biochar alters the selectivity of MnFeO-activated periodate process through serving as the electron-transfer mediator.

Constructing green and sustainable advanced oxidation processes (AOPs) for the degradation of organic contaminants is of great importance but still remains big challenge. In this work, an effective AOP (MnFeO-activated periodate, MnFeO/PI) was established and investigated for the oxidation of organic contaminants. To avoid the severe aggregation of MnFeO nanoparticles, a hybrid MnFeO-biochar catalyst (MnFeO-BC) was further synthesized by anchoring MnFeO nanoparticles on chemically inert biochar substrate.

Molecular Imaging of Fibrosis in Benign Diseases: An Overview of the State of the Art.

Fibrosis is a progressive pathological process participating in the progression of many diseases and can ultimately result in organ malfunction and failure. Around 45% of deaths in the United States are believed to be attributable to fibrotic disorders, and there are no favorable treatment regiments available to meet the need of blocking fibrogenesis, reversing established fibrosis, and curing diseases, especially in the terminal stage. Therefore, early detection and continuous monitoring provide valuable benefits for patients.

Effect of DBD Plasma Treatment on Activity of Mo-Based Sulfur-Resistant Methanation Catalyst.

By combining the advantages of dielectric barrier discharge (DBD) low temperature plasma and fluidized bed, the effect of plasma on the performance of supported Mo-based catalyst was studied in this paper. The performance of the catalyst obtained by plasma treatment, calcined, plasma+calcined was compared, and the appropriate catalyst preparation scheme was explored. Comparing with the three catalysts, it was concluded that the catalyst average conversion after 30 W plasma treatment is 33.

Association between GSTP1 I105V polymorphisms and responses to GSTP1 inhibitor treatment: in silico and in vitro insights.

Glutathione S-transferase P1 (GSTP1) has gradually become a promising target for cancer prevention and treatment. However, subtle variations in GSTP1 can lead to the occurrence of single nucleotide polymorphisms (SNPs). The correlation between specific genotypes of GSTP1 and the clinical outcome of the disease has been extensively investigated, demonstrating a significant area of research in this field.

Adenoma location, size, and morphology are risk factors for FOBT false-negative results in inpatients with advanced colorectal adenoma.

Recently, advanced adenoma (AA) has been recognized as a target for colorectal cancer (CRC) screening. However, the fecal occult blood test (FOBT), the primary non-invasive screening method, shows limited sensitivity in detecting AA. This study investigates the relationship between adenoma characteristics and FOBT false-negative results.

Study on Magnetization Roasting Kinetics of High-Iron and Low-Silicon Red Mud.

High-iron and low-silicon red mud is not only an alkaline solid waste from Bayer process alumina production, but it is also a very important secondary iron resource. Magnetization roasting is considered as an effective and typical method for the iron recovery and removal of impurities in red mud. In this work, based on the characteristics of large specific surface area and high porosity of red mud, the kinetics of magnetization roasting and phase transformation of red mud were studied.

Alpha-fetoprotein-elevated postpubertal testicular teratoma with retroperitoneal metastasis on F-FDG PET/CT: case report and literature review.

Postpubertal testicular teratoma exhibits malignant biological behavior and has metastatic potential. We report a case of a 17-year-old patient diagnosed with postpubertal testicular teratoma with massive retroperitoneal metastasis. The pathological examination revealed a mature teratoma without any other components.

F-FDG PET/CT imaging of primary malignant melanoma of rectum with liver metastases mimicking rectum cancer: case report and literature review.

Malignant melanoma (MM) is an aggressive malignant tumor, which mostly occurs on the skin, uvea, etc. The mucosal MM accounts for a small proportion of all MM and can occur in the digestive tract. Primary MM of the digestive tract is rare and can be found in the middle and lower third of the esophagus and the rectum containing melanocytes.

Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling.

Background And Purpose: Squalene epoxidase (SQLE) is a key enzyme involved in cholesterol biosynthesis, but growing evidence also reveals that SQLE is abnormally expressed in some types of malignant tumours, even though the underlying mechanism remains poorly understood.

Experimental Approach: Bioinformatics analysis and RNA sequencing were applied to detect differentially expressed genes in clinical hepatocellular carcinoma (HCC). MTT, colony formation, AnnexinV-FITC/PI, EdU, wound healing, transwell, western blot, qRT-PCR, IHC, F-actin, RNA-sequencing, dual-luciferase reporters, and H&E staining were used to investigate the pharmacological effects and possible mechanisms of SQLE.

An Optimization-Based Motion Planner for Car-like Logistics Robots on Narrow Roads.

Thanks to their strong maneuverability and high load capacity, car-like robots with non-holonomic constraints are often used in logistics to improve efficiency. However, it is difficult to plan a safe and smooth optimal path in real time on the restricted narrow roads of the logistics park. To solve this problem, an optimization-based motion planning method inspired by the Timed-Elastic-Band algorithm is proposed, called Narrow-Roads-Timed-Elastic-Band (NRTEB).

Retroperitoneal alveolar rhabdomyosarcoma intruding into spinal canal: A case report and literature review.

Background: Rhabdomyosarcoma (RMS) is the most frequent soft sarcoma in children and adolescents. Alveolar rhabdomyosarcoma (ARMS) is a relatively rare subtype that is characterized by aggressive behavior and an unsatisfactory prognosis. An ARMS can arise anywhere but most commonly occurs at extremity sites with a very small fraction in the retroperitoneum.

SGSNet: A Lightweight Depth Completion Network Based on Secondary Guidance and Spatial Fusion.

The depth completion task aims to generate a dense depth map from a sparse depth map and the corresponding RGB image. As a data preprocessing task, obtaining denser depth maps without affecting the real-time performance of downstream tasks is the challenge. In this paper, we propose a lightweight depth completion network based on secondary guidance and spatial fusion named SGSNet.

A rare B-cell type chronic active Epstein-Barr virus infection patient mimicking lymphoma on F-FDG PET/CT and literature review.

A 13-year-old girl suffered from worsen snoring and persistent bilateral nasal congestion for one year. Paranasal sinus computed tomography (CT) and magnetic resonance imaging (MRI) found nasopharyngeal passages and sinus were occupied with soft tissues and bilateral neck enlarged lymph nodes 6 months ago. Tumor markers were normal.

Degradation of pefloxacin by hybrid hydrodynamic cavitation with HO and O.

The degradation of toxic chemicals, antibiotics and other residues in organic wastewater has attracted much attention. Among various degradation technologies, hydrodynamic cavitation (HC) reactors have the advantage of being simple to operate. Through the combination of HC and other oxidants, the removal efficiency and energy efficiency of organic matter can be greatly improved, and the consumption of chemicals and the processing costs can be reduced.

Effect of S-ketamine on Postoperative Quality of Recovery in Patients Undergoing Video-Assisted Thoracic Surgery.

Objectives: S-ketamine is associated with effective postoperative analgesia and enhanced quality of recovery (QoR). The study aimed to investigate the effect of perioperative S-ketamine on postoperative quality of recovery in patients undergoing video-assisted thoracic surgery (VATS).

Design: A prospective, randomized, double-blinded, placebo-controlled trial.

Intelligent Bus Platoon Lateral and Longitudinal Control Method Based on Finite-Time Sliding Mode.

Considering the rapid convergence of the longitudinal and lateral tracking errors of the platoon, a finite-time tracking control method for the longitudinal and lateral directions of the intelligent bus platoon is proposed. Based on the bus platoon model and desired motion trajectory, a distributed longitudinal and lateral finite-time sliding mode tracking control framework of the platoon is designed. Considering the finite-time convergence of the sliding mode of the system, a nonsingular integral terminal sliding mode (NITSM) is designed.

Importin 13 promotes NSCLC progression by mediating RFPL3 nuclear translocation and hTERT expression upregulation.

Our previous studies have reported that RFPL3 protein exerts its unique function as a transcriptional factor of hTERT promoter after being transported into the lung cancer cell nucleus. However, the detailed mechanism by which RFPL3 undergoes nuclear transport has not been reported yet. Here, we identified RFPL3 as a potential import cargo for IPO13, which was found to be overexpressed in NSCLC cells and tissues.

Sodium Arsenite Inhibits Lung Fibroblast Differentiation and Pulmonary Fibrosis.

Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease with a high mortality and poor prognosis. Transforming growth factor (TGF)-β plays crucial roles in the pathogenesis of IPF. To investigate the role of sodium arsenite (SA) on fibroblast differentiation and pulmonary fibrosis, we checked the effects of SA on TGF-β-induced normal human lung fibroblasts (NHLFs) differentiation, and the anti-fibrotic effect of SA on bleomycin (BLM)-induced pulmonary fibrosis in mouse.

An Established HPLC-MS/MS Method for Evaluation of the Influence of Salt Processing on Pharmacokinetics of Six Compounds in Cuscutae Semen.

A sensitive and effective method was developed for clarifying the pharmacokinetic properties of six compounds (including hyperin, chlorogenic acid, neochlorogenic acid, p-coumaric acid, astragalin, and isoquercitrin) in two processed Cuscutae Semen samples by high performance liquid chromatography mass spectrometry (HPLC-MS/MS). The six compounds were separated by acetonitrile and 0.1% formic acid-water on an Agilent Eclipse plus C18 column (4.