Publications by authors named "Hao Huai"
Article Synopsis
- The study compares two cultivars of a traditional Chinese medicine, 'Miaoxiang Sanqi No. 2' (yellow root) and 'Wenyuan Ziqi No. 1' (purple root), focusing on their morphological, transcriptional, and metabolic differences.
- It was found that 'Wenyuan Ziqi No. 1' has a higher accumulation of anthocyanins, particularly cyanidin 3-O-galactoside, leading to its purple coloration, and contains 155 different metabolites, including flavones and phenylpropanoids.
- The research highlights the strong expression of phenylpropanoid biosynthesis pathway genes and identifies eight genes potentially involved in anthocyanin
Article Synopsis
- A reference genome for a medicinal plant affected by root rot was created, revealing 66 candidate disease-resistance genes for breeding purposes.
- The study analyzed gene expression in resistant and susceptible plant genotypes during infection, showing that defense-related genes were highly active in the resistant plants.
- Increased levels of salicylic acid and jasmonic acid were noted in resistant plants, with a key gene identified that plays a central role in their defense responses.
Background: Neurogenin2 (Ngn2) is a proneural gene that directs neuronal differentiation of progenitor cells during development. Here, we investigated whether Ngn2 can reprogram MSCs to adopt a neural precursor fate and enhance the therapeutic effects of MSCs after experimental stroke.
Methods: In vitro, MSCs were transfected with lenti-GFP or lenti-Ngn2.