Effect of High Molecular Weight PPTA on Liquid Crystalline Phase and Spinning Process of Aramid Fibers.

High molecular weight poly (-phenylene-terephthalamide) (h-PPTA) was blended with the commercial PPTA in concentrated sulfuric acid to improve the spinnability of the polymer solutions and the mechanical properties of the as-spun fibers. h-PPTA in the solution has an influence on the temperature of the formation of liquid crystalline phenomenon. The temperature range with the existence of the liquid crystalline phase increases upon the contents of h-PPTA in the solution, and the extended temperature window is helpful for the preparation of PPTA fibers by the dry-jet wet-spinning technology.

Metabolism of insecticide diazinon by ATCC36112.

The fungal metabolism of diazinon was investigated and the microbial model ( ATCC36112) could effectively degrade the organophosphorus pesticide (diazinon) mediated by cytochrome P450, which was mainly involved in oxidation and hydrolysis of phase I metabolism. Approximately 89% of diazinon was removed within 7 days and was not observed after 13 days with concomitant accumulation of eight metabolites. Structures of the metabolites were fully or tentatively identified with GC-MS and H, C NMR.

Giant congenital melanocytic nevus of the scalp: from clinical-histological to molecular diagnosis.

Congenital melanocytic nevus (CMN) is a benign proliferative skin disease in the epidermis and dermis. Large to giant CMNs are estimated to be associated with an increased lifetime risk of malignancy. It is necessary to estimate and monitor the risk of malignant transformation for giant CMNs.

MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells.

The connections between energy metabolism and stemness of hematopoietic stem cells (HSCs) at different developmental stages remain largely unknown. We generated a transgenic mouse line for the genetically encoded NADH/NAD+ sensor (SoNar) and demonstrate that there are 3 distinct fetal liver hematopoietic cell populations according to the ratios of SoNar fluorescence. SoNar-low cells had an enhanced level of mitochondrial respiration but a glycolytic level similar to that of SoNar-high cells.

Transcriptome Profiling of Lung Innate Immune Responses Potentially Associated With the Pathogenesis of Acute Lethal Pneumonia.

is one of the dominating causes of nosocomial pneumonia, however, very little is known about the host immune response associated with pathogenesis of infection. Here, we used a hypervirulent to establish an acute lethal pneumonia, supported by high bacterial burdens, severe inflammatory cells infiltration and lung damage. The lung transcriptome changes in response to lethal pneumonia were detected by RNA sequencing.

Maternal microchimerism protects hemophilia A patients from inhibitor development.

Deleterious mutations do not necessarily lead to the incidence of inhibitors in hemophilia A patients receiving replacement therapy. Maternal chimeric cells migrated into a fetus with hemophilia A during pregnancy could induce tolerance toward FVIII.

Tailoring Component Interaction for Air-Processed Efficient and Stable All-Inorganic Perovskite Photovoltaic.

All-inorganic lead halide perovskites are promising candidates for optoelectronic applications. However, fundamental questions remain over the component interaction in the perovskite precursor solution due to the limitation of the most commonly used solvents of N,N-dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). Here, we report an interaction tailoring strategy for all-inorganic CsPbI Br perovskites by involving the ionic liquid solvent methylammonium acetate (MAAc).

Ni and Zn co-substituted Co(CO)OH self-assembled flowers array for asymmetric supercapacitors.

The supercapacitive performance of high-rate capacity and long-term cycling stability is still a big challenge for electroactive materials. Herein, Ni and Zn co-substituted Co carbonate hydroxide (NiZn-CoCH) flowers array is self-assembled on nickel foams (NFs) using l-ascorbic acid as a nanostructure inducer. The NiZn-CoCH flowers, consisting of silk-like nanosheets, are deservedly large electrode-electrolyte contact area and suitable ion-diffusion channel.

Interim results of bleomycin-polidocanol foam sclerotherapy as a highly efficient technique for venous malformations.

Objective: The objective of this study was to retrospectively review the clinical and radiographic outcomes of patients with venous malformations (VMs) treated with bleomycin-polidocanol foam (BPF) sclerotherapy.

Methods: The Institutional Review Board waived ethical approval for this retrospective review in which 55 patients (31 female and 24 male patients; mean age, 18.8 years; range, 2-60 years) were treated with BPF sclerotherapy.

Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.

Nemo-like kinase (NLK), an evolutionarily conserved serine/threonine kinase, is highly expressed in the brain, but its function in the adult brain remains not well understood. In this study, we identify NLK as an interactor of huntingtin protein (HTT). We report that NLK levels are significantly decreased in HD human brain and HD models.

Divergence and Convergence of Cerebral Ischemia Pathways Profile Deciphers Differential Pure Additive and Synergistic Mechanisms.

Aim: The variable mechanisms on additive and synergistic effects of jasminoidin (JA)-Baicalin (BA) combination and JA-ursodeoxycholic acid (UA) combination in treating cerebral ischemia are not completely understood. In this study, we explored the differential pure mechanisms of additive and synergistic effects based on pathway analysis that excluded ineffective interference.

Methods: The MCAO mice were divided into eight groups: sham, vehicle, BA, JA, UA, Concha Margaritifera (CM), BA-JA combination (BJ), and JA-UA combination (JU).

[Structural variations caused by transposons in porcine ktn1 gene and their association with production traits].

In order to determine the effect of transposons on the sequence and structural variations of the porcine ktn1 gene and its flanking regions, we obtained 14 ktn1 sequences (including genic region, 5-kb 5' flank and 3-kb 3' flanking regions) from the WGS database in NCBI, multiple sequence alignment by ClustalX and transposon annotation by RepeatMasker. Then we analyzed the effect of transposons on ktn1. A SINEA1 insertion polymorphism was detected by PCR, and correlation was analyzed with related traits in the Sujiang pig population.

Long non-coding RNA HOTAIR knockdown enhances radiosensitivity through regulating microRNA-93/ATG12 axis in colorectal cancer.

Colorectal cancer (CRC) is a global healthcare problem. Radioresistance is a huge setback for CRC radiotherapy. In this text, the roles and molecular mechanisms of long non-coding RNA HOTAIR in CRC tumorigenesis and radioresistance were further investigated.

Bleomycin Polidocanol Foam (BPF) Stability - In Vitro Evidence for the Effectiveness of a Novel Sclerosant for Venous Malformations.

Objective: This study investigated the in vitro stability of a novel sclerosant, bleomycin polidocanol foam (BPF), for venous malformation (VM) sclerotherapy.

Methods: The study was designed with control groups treated with polidocanol (0.5%, 1%, and 3%) only.

A New Model of Repetitive Traumatic Brain Injury in Mice.

Repetitive traumatic brain injury (rTBI) is a major health care concern that causes substantial neurological impairment. To better understand rTBI, we introduced a new model of rTBI in mice induced by sudden rotation in the coronal plane combined with lateral translation delivered twice at an interval of 24 h. By routine histology, histological examination of Prussian blue-stained sections revealed the presence of microbleed in the corpus callosum and brain stem.

Spontaneous and Dramatic Improvements in Open Bite Deformity Secondary to Large Maxillofacial Venous Malformation With Macroglossia After Sclerotherapy and Laser Therapy.

Background: Large maxillofacial venous malformation (VM) lesions can affect the craniofacial skeleton, causing occlusal and craniofacial deformity. Few studies have discussed the management of these skeletal disorders. It is unclear whether orthodontic treatment and orthognathic surgery are necessary after such a VM lesion has been significantly reduced.

Nitric Oxide-Generating Antiplatelet Polyurethane Surfaces with Multiple Additional Biofunctions via Cyclodextrin-Based Host-Guest Interactions.

A nitric oxide-generating polymeric coating was prepared by copolymerization of the hydrophilic monomer 2-hydroxyethyl methacrylate (HEMA) and the comonomer 1-adamantan-1-ylmethyl methacrylate (AdaMA) with subsequent incorporation of selenocystamine. The coating was applied to polyurethane (PU) as a substrate. In the presence of a NO donor, the PU-PHA-Se surface generated nitric oxide (NO).

Alternative polyadenylation of the stacyose synthase gene mediates source-sink regulation in cucumber.

Alternative polyadenylation (APA) is a pervasive mechanism for gene regulation in eukaryotes. Stachyose is the main assimilate translocated in the cucumber phloem. Stachyose synthase (CsSTS) catalyzes the last step of stachyose biosynthesis in cucumber leaves and plays a key role in the regulation of assimilate partitioning between source and sink.

Improved Long Ureteral Reconstruction With Ileum By Longitudinal Clipping And Mucosal Stripping: An Animal Study.

Purpose: To investigate the possibility of bridging long ureteral defects by longitudinal clipping and mucosal stripping of the pedicled segment of ileum (CMSPI).

Materials And Methods: Ten beagle dogs (five males and females aged 2-3 years) were used to model a defect of the entire ureter. An ileal segment was selected, and half of the intestinal segment was longitudinally resected, without mesenteric resection.

[Multi-dimensional mining and analysis of core prescriptions in launched Chinese patent medicine for treatment of influenza].

Through the multi-dimensional mining and analysis of launched anti-influenza proprietary Chinese medicines,this paper explores the study of the prescriptions and pharmacodynamics of traditional Chinese medicines for influenza. We established a standardized database by collecting and excavating the launched Chinese patent medicines that clearly describe the treatment of influenza. Frequency analysis and association rules were used to analyze the frequency of Chinese patent medicines for the treatment of influenza in the aspects of dosage form,category and prescription drugs.

CircRNA_100367 regulated the radiation sensitivity of esophageal squamous cell carcinomas through miR-217/Wnt3 pathway.

Background: Circular RNAs (circRNAs) play important roles in regulating the radioresistance of esophageal squamous cell carcinoma (ESCC). This study aimed to determine the role of hsa_circRNA_100367 in regulating radioresistance of ESCC.

Results: Higher expression and potency of endothelial to mesenchymal transformation (EMT) was found in radioresistant ESCC cells (KYSE-150R) than in ESCC cells (KYSE-150).

Poly(ethylene terephthalate) Powder-A Versatile Material for Additive Manufacturing.

The 3D printing of articles by the effect of a directed laser beam on a plastic powder is a demanding process, and unlike injection molding, very few polymers work well enough with it. Recently, we reported that poly(ethylene terephthalate) (PET) powder has intrinsically good properties for 3D printing. Basic mechanical properties were shown earlier and it was demonstrated that unfused but heat-exposed PET powder does not degrade quickly allowing good re-use potential.

circCDYL/microRNA-105-5p participates in modulating growth and migration of colon cancer cells.

Circular RNA-microRNA (circRNA-miR) node has recently been found to modulate cancer process. Here, we investigated whether circCDYL and miR-150-5p exerted biological function in colon cancer cells. Colon cancer tissues were collected and subjected to qRT-PCR assay for circCDYL and miR-150-5p.

Red-Carbon-Quantum-Dot-Doped SnO Composite with Enhanced Electron Mobility for Efficient and Stable Perovskite Solar Cells.

An efficient electron transport layer (ETL) plays a key role in promoting carrier separation and electron extraction in planar perovskite solar cells (PSCs). An effective composite ETL is fabricated using carboxylic-acid- and hydroxyl-rich red-carbon quantum dots (RCQs) to dope low-temperature solution-processed SnO , which dramatically increases its electron mobility by ≈20 times from 9.32 × 10 to 1.