Evaluation of the biocompatibility, antibacterial and anticancer effects of a novel nano-structured Fe-Mn-based biodegradable alloys in-vitro study.

Scientific Backgrounds: Development of nanostructured biodegradable alloys has generated a great deal of interest in the recent years as they offer promising bioactive materials for reconstruction of bony defects following traumatic fractures or surgical excision of tumors.

Objectives: The aim of the current study was to investigate the biocompatibility of Iron-Manganese -based alloys (Fe-Mn) with addition of copper (Cu), Tungsten (W) and cobalt (Co) to obtain 3 different alloys namely, Fe-Mn-Cu, Fe-Mn-W, and Fe-Mn-Co on normal oral epithelial cell line,and their possible anticancer effect on MG-63: osteosarcoma cell line.

Materials And Methods: The sulforhodamine B (SRB) assay was used to assess cell viability percentage of both cell lines after exposure to discs of the proposed experimental alloys.

Comparing biological and physical cost functions in VMAT planning for pediatric nasopharyngeal cancer.

Background: Volumetric Modulated Arc Therapy (VMAT) is an option for the delivery of Radiotherapy treatment technique for pediatric nasopharyngeal cancer, VMAT is the most common treatment technique for pediatric nasopharyngeal cancer. The use of a combination of both biological and physical parameters in VMAT planning optimization may produce better target coverage and sparing of critical organs. This work was to compare Biological Cost Functions (BCFs) and Physical Cost Functions (PCFs) in the VMAT of pediatric nasopharyngeal cancer patients.

Effect of AlO (x = 0, 1, 2, and 3 vol.%) in CrFeCuMnNi-x High-Entropy Alloy Matrix Composites on Their Microstructure and Mechanical and Wear Performance.

This work aims to study the influence of AlO in CrFeCuMnNi high-entropy alloy matrix composites (HEMCs) on their microstructure, phase changes, and mechanical and wear performances. CrFeCuMnNi-AlO HEMCs were synthesized via mechanical alloying (MA) followed by hot compaction (550 °C at 550 MPa), medium frequency sintering (1200 °C), and hot forging (1000 °C at 50 MPa). The XRD results demonstrate the formation of both FCC and BCC phases in the synthesized powders, which were transformed into major stable FCC and minor ordered B2-BCC phases, as confirmed by HRSEM.

Synthesis, Microstructure Investigation, Mechanical and Tribological Behaviour of the AA5083-WC Composite.

In this study, AA5083-WC composites were developed by ball milling followed by hot consolidation. The microstructures of the developed composites were investigated using XRD, SEM, EDX, and EBSD. The developed composites exhibited a homogeneous dispersion of WC particulates in the AA5083 matrix without any interactions at the matrix/reinforcement interface.

Prognostic factors affecting infantile medulloblastoma outcomes in the molecular era: a 12-year single-center experience from Egypt.

To assess the clinical, pathological and molecular characteristics (Sonic hedgehog and group 3/4 molecular subtypes expression) and treatment modalities for infantile medulloblastoma in correlation with outcomes. A retrospective study of 86 medulloblastoma patients (≤3 years) was conducted. M0 patients <2.

Voluntary deep inspiration breath-hold with volumetric modulated arc therapy in pediatric patients with mediastinal Hodgkin lymphoma.

Deep inspiration breath-hold (DIBH) has been established to decrease normal tissue radiation dose in breast cancer. Forty-nine patients had two CT scans during DIBH or free breathing. Chest-wall position, setup verification and breath-hold monitoring were performed.

Developing Improved Corrosion-Resistant AA5083-BN/WC Composites for Tribological Applications.

In this study, corrosion-resistant AA5083-BN/WC composites were developed for tribological applications through adequate control of the reinforcement content (WC and BN) in the matrix (AA5083 alloy). The effects of 6% and 12% tungsten carbide (WC) as well as 6% and 12% boron nitride (BN) additions on the corrosion behavior of AA5083 aluminum composite in 3.5% NaCl solution were carried out.

Investigation of the Microstructure and Compressibility of Biodegradable Fe-Mn-Cu/W/Co Nanostructured Alloy Powders Synthesized by Mechanical Alloying.

In this research work, the nanostructured Fe-Mn (BM0), Fe-Mn-Cu (BM1), Fe-Mn-W (BM2), and Fe-Mn-Co (BM3) biodegradable alloys were successfully synthesized using mechanical alloying. The microstructure of the synthesized alloys was examined using XRD, SEM equipped with EDS, and HRTEM techniques. The results obtained based on these techniques confirmed the development of nanostructured BM0, BM1, BM2, and BM3 alloys and homogenous solid solutions with an even elemental dispersion.

Noninvasive assessment of human jawbone using ultrasonic guided waves.

The problem of detecting defects in jawbones is an important problem. Existing methods based on Xrays are invasive and constrain the achievable image quality. They also may carry known risks of cancer generation or may be limited in accurate diagnosis scope.