Publications by authors named "Hanxiang Zhong"
Article Synopsis
- ADAR1 is an RNA-editing enzyme that shows varying expression across different cancer types, especially lower in certain kidney cancers and higher in liver cancer compared to normal tissues.
- Validation techniques, including RT-PCR and western blotting, confirmed these expression patterns and their correlation with patient prognosis in kidney and liver cancers.
- The study identified distinct relationships between ADAR1 expression and specific stromal cell types, notably revealing inverse relationships with the gene claudin-5 in kidney and liver cancer samples.
Article Synopsis
- * Lymphatic endothelial cells (LECs) and blood endothelial cells (BECs) are crucial not just for structural support but also for processes like blood vessel formation (angiogenesis), lymph vessel formation (lymphangiogenesis), and immune response modulation.
- * The review focuses on the intricate interactions between LECs, BECs, and tumor cells, highlighting their roles in HCC and proposing future research and treatment avenues based on the immune functions of these endothelial cells.
Non-alcoholic fatty liver disease (NAFLD) is a complex disease characterized by a massive accumulation of lipids in the liver, with a continuous progression of simple steatosis, non-alcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma. Non-alcoholic fatty liver disease is associated with obesity, insulin resistance, and metabolic syndrome; it is a severe public health risk and is currently the most common liver disease of the world. In addition to the fatty infiltration of the liver in non-alcoholic fatty liver disease patients, the field of liver transplantation faces similar obstacles.
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