Microplastics in maternal blood, fetal appendages, and umbilical vein blood.

Microplastics (MPs) have been detected in placenta and amniotic fluid, but there is no research on whether MPs exist in the other two fetal appendages: fetal membrane and umbilical cord. Additionally, the existence of MPs in umbilical vein blood remains unexplored. Furthermore, it is unclear whether MPs in maternal blood are associated with those in umbilical vein blood and fetal appendages.

Association of different types of abortions with neonatal outcomes in subsequent pregnancy.

Background: Abortion is an important issue that concerns all women. It holds great significance to investigate the correlation between various types of abortion histories and the neonatal outcomes of subsequent pregnancies.

Methods: This retrospective cohort study included pregnant women who gave birth to singleton live-born in Shanghai First Maternity and Infant Hospital from 2016 to 2020 (n = 75 773).

Regulation of the Function and Expression of EpCAM.

The epithelial cell adhesion molecule (EpCAM) is a single transmembrane protein on the cell surface. Given its strong expression on epithelial cells and epithelial cell-derived tumors, EpCAM has been identified as a biomarker for circulating tumor cells (CTCs) and exosomes and a target for cancer therapy. As a cell adhesion molecule, EpCAM has a crystal structure that indicates that it forms a cis-dimer first and then probably a trans-tetramer to mediate intercellular adhesion.

Impact of spontaneous abortion history and induced abortion history on perinatal outcomes of singleton pregnancies.

Background: At present, there are several studies on abortion history and perinatal outcomes, but there is no unified conclusion whether the history of abortion and different types of abortion are related to perinatal complications of subsequent pregnancy. We aim to study the impact of different types of abortion history on perinatal outcomes of singleton pregnancies.

Methods: This was a retrospective study from a maternity and infant hospital in Shanghai, China from 2016 to 2020.

Impact of pre-pregnancy weight on the risk of premature rupture of membranes in Chinese women.

Objective: The objective of this study was to investigate the influence of pre-pregnancy body mass index (BMI) on the incidence of premature rupture of membranes (PROM) among Chinese women.

Methods: This was a hospital-based retrospective cohort study of 75,760 Chinese women who had live singleton births between 2016 and 2020. In this study, we utilized logistic regression analysis to estimate the association between pre-pregnancy BMI and PROM based on gestational age.

relieves intrahepatic cholestasis of pregnancy through bile acid/FXR-FGF15 in rats.

Previous research has demonstrated significant differences in intestinal flora between pregnant women with intrahepatic cholestasis of pregnancy (ICP) and healthy pregnant women. The objective of our study is to identify the key bacteria involved in ICP rats and explore the underlying mechanism. We established an ICP rat model and collected rat feces for metagenomic sequencing and found that (R.

Association between Abortion History and Perinatal and Neonatal Outcomes of Singleton Pregnancies after Assisted Reproductive Technology.

Importance: At present, few people have studied the associations between abortion history before pregnancy on the outcomes of women and their infants after assisted reproductive technology (ART).

Objective: To explore the association between the history of abortion and the outcomes of singleton pregnancies after ART.

Design: This was a retrospective study in a hospital from 2015 to 2020 in Shanghai, China.

Association between cervical disorders and adverse obstetric outcomes: A retrospective cohort study.

Objective: The purpose of this study was to explore the association of cervical disorders on obstetric outcomes of singleton pregnancies in China.

Methods: This hospital-based retrospective cohort study of women with live singleton births included 71,097 Chinese women. We compared the risk of adverse obstetric outcomes in different types of pregnancies with cervical disorders with those with normal cervix.

Association Between Pre-Pregnancy Body Mass Index and Maternal and Neonatal Outcomes of Singleton Pregnancies After Assisted Reproductive Technology.

Objective: To study the association between pre-pregnancy body mass index (BMI) and adverse maternal and neonatal outcomes of singleton pregnancies after assisted reproductive technology (ART).

Methods: This hospital-based retrospective cohort study of women with live singleton births through ART in China from January 2015 to August 2020 included 3043 Chinese women. According to the latest BMI classification standard of Asian women, the women included in this study were classified as underweight (BMI <18.