In vitro antimicrobial activity of oxidized regenerated cellulose against antibiotic-resistant microorganisms.

Background: The emergence of multi-drug resistant microorganisms presents a critical problem for patients undergoing surgery. Acidic pH, which is produced by oxidized regenerated cellulose (ORC), is a broad-spectrum physiological detriment to survival of microorganisms known to cause surgical infections. The purpose of this study was to examine the antimicrobial effect of ORC against antibiotic-resistant organisms.