Implementing a new antibiotic allergy protocol in clinical practice: well-trusted but not used.

Background: Suboptimal antibiotic prescriptions in patients with an antibiotic allergy label lead to increased incidence of adverse events and antimicrobial resistance (AMR). An antibiotic allergy protocol was developed in a Dutch academic hospital guiding optimal and safe antibiotic use in potentially penicillin-allergic patients. Informed by previous studies of implementation processes in clinical care, we studied the implementation of this protocol.

[Vaccination refusal; the need for positive influence strategies].

Although vaccinating seems self-evident, the immunization coverage in the Netherlands is decreasing. This decrease is often attributed to a lack of knowledge amongst the public. We argue, however, that it is rather a lack of trust that drives this reduction in uptake.

Adolescent's weight concerns and the onset of smoking.

The hypothesis that adolescents start smoking because they perceive it as a strategy to control their weight was examined. At the same time, we controlled for sociodemographic, individual, and parental factors. Longitudinal data were collected among 428 Dutch families (mother, father, and two siblings between 13 and 16 years of age) in two measurements: the first in 2002-2003 and the second a year later.

Role of bacterial vaginosis-associated microorganisms in endometritis.

Objective: Our goal was to define the role of bacterial vaginosis and bacterial vaginosis-associated microorganisms in endometritis.

Study Design: Endometrial biopsies were obtained for histologic and microbiologic study from 178 consecutive women with suspected pelvic inflammatory disease, and 85 of them underwent laparoscopy to diagnose salpingitis.

Results: Histologic endometritis was confirmed in 117 (65%) of the women.