Publications by authors named "Hanshan Xu"

Article Synopsis
  • Time-dependent diffusion MRI is being studied for its potential to noninvasively predict tumor properties and patient outcomes in breast cancer, focusing on molecular subtypes and pathologic complete response (pCR).
  • A study involving 408 breast cancer participants analyzed microstructural parameters and ADC measurements to develop a predictive model, with results demonstrating the MRI technique's ability to identify different breast cancer subtypes effectively.
  • The predictive model showed high performance for HER2-enriched breast cancer (AUC 0.85) and better results compared to traditional ADC measurements, indicating its significance in clinical evaluations for breast cancer treatment.
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Objectives: To investigate the feasibility of T1rho-weighted imaging in differentiating malignant from benign breast lesions and to explore the additional value of T1rho to conventional MRI.

Materials And Methods: We prospectively enrolled consecutive women with breast lesions who underwent preoperative T1rho-weighted imaging, diffusion-weighted imaging, and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) between November 2021 and July 2023. The T1rho, apparent diffusion coefficient (ADC), and semi-quantitative parameters from DCE-MRI were obtained and compared between benign and malignant groups.

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As the main source of energy for human beings, starch is widely present in people's daily diet. However, due to its high content of rapidly digestive starch, it can cause a rapid increase in blood glucose after consumption, which is harmful to the human body. In the current study, the complexes made from edible rose polyphenols (ERPs) and three starches (corn, potato and pea) with different typical crystalline were prepared separately by multi-frequency power ultrasound (MFPU).

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Background: Determining the status of lymph node (LN) metastasis in rectal cancer patients preoperatively is crucial for the treatment option. However, the diagnostic accuracy of current imaging methods is low.

Purpose: To develop and test a model for predicting metastatic LNs of rectal cancer patients based on clinical data and MR images to improve the diagnosis of metastatic LNs.

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Objectives: This study aimed to evaluate the feasibility and reproducibility of using cardiovascular magnetic resonance feature tracking (CMR-FT) for analysis of bi-ventricular strain and strain rate (SR) in hypertrophic cardiomyopathy (HCM) patients as well as to explore the correlation between right ventricular (RV) and left ventricular (LV) deformation.

Methods: A total of 60 HCM patients and 48 controls were studied. Global and segmental peak values of bi-ventricular longitudinal, circumferential, radial strain, and systolic SR were analyzed.

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Rationale And Objectives: This study was designed to assess left ventricular deformation after chronic myocardial infarction (CMI) using cardiac magnetic resonance feature tracking (CMR-FT) technology, and analyze its relationship with left ventricular ejection fraction (LVEF) and infarcted transmurality.

Materials And Methods: Ninety-six patients with CMI and 72 controls underwent 3.0 T CMR scanning.

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Rice starch-Gallic acid (GA) complex (RSP-GA) was prepared by high pressure homogenization (HPH), and the effect of GA on the digestibility and multi-structure of rice starch under HPH was investigated. The results showed that, after HPH, the digestibility of starch substantially changed in the reduced rapidly digestible starch (RDS) content, and increased resistant starch (RS) after interacting with GA. In particular, the RS content of RSP-GA ranged from 5.

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As a major sterol in edible mushroom, ergosterol has gained much attention owing to its potential bioactivities. However, ergosterol has a high melting point, poor oil solubility and stability, which restrict its scope of application. In this study, an ergosterol ester of α-linolenic acid was successfully and efficiently prepared using Candida sp.

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Ergosterol and its derivatives have attracted much attention for a variety of health benefits, such as anti-inflammatory and antioxidant activities. However, ergosterol esters are advantageous because this compound has better solubility than the free ergosterol. In this work, ergosterol laurate was efficiently synthesized for the first time by direct esterification in a solvent-free system.

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