A standalone approach to utilize telomere length measurement as a surveillance tool in oral leukoplakia.

Oral squamous cell carcinoma (OSCC) is often preceded by a white patch on a surface of the mouth, called oral leukoplakia (OL). As accelerated telomere length (TL) shortening in dividing epithelial cells may lead to oncogenic transformation, telomere length measurement could serve as a predictive biomarker in OL. However, due to high variability and lack of a universal reference, there has been a limited translational application.

Detection of Connexion 26 GENE (GJB2) Mutations in Cases of Congenital Non Syndromic Deafness.

Hearing loss is most common form of genetic hearing disorder. Non-syndromic sensory neural autosomal recessive deafness (NSRD) is the most common form of genetic hearing loss. Mutations in GJB2 gene, which encodes the connexin 26 protein, are major cause of NSRD.

Objective and subjective evaluation of larynx in smokers and nonsmokers: a comparative study.

The deleterious effects of smoking on laryngeal mucosa are indisputable. Smoking not only causes histologic (microscopic) alterations in the vocal fold epithelium but also affect the acoustic property of voice. The goal of this study was to determine the effects of smoking on the laryngeal structures and phonatory physiology via videostroboscopy, acoustic voice analysis and electroglottography.

Demographic and videostroboscopic assessment of vocal pathologies.

Successful treatment of bilateral vocal fold lesions depends on the accuracy of the diagnosis. The application of stroboscopy to the study of vocal fold vibration has led to dramatic advances in the understanding of vocal fold physiology. Laryngeal stroboscopy is the state of the art diagnostic tool and this technique provides valuable information about the nature of the vibration and a visual image that can be used both for immediate analysis and as a permanent record for comparison of repeated examination at a later date.

Bronchial rhinosporidiosis: An unusual presentation.

Rhinosporidiosis is a granulomatous disease that usually affects the nasal mucosa and nasopharynx. The disease is widely prevalent in the tropics, especially in southern India and Sri Lanka. In central India, rhinosporidiosis is endemic in Raipur, Chhattisgarh.