Publications by authors named "Hans-Joachim Schafers"

Objectives: The Ross procedure is currently receiving renewed interest. Its function and durability depend on preservation of pulmonary valve anatomy; limited data exist on normal pulmonary valve geometry. The objective was to compare aortic and pulmonary root and cusp dimensions in adults with normal tricuspid aortic and pulmonary valves.

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Bicuspid aortic valves may be associated with coronary anomalies. We report a case of a regurgitant bicuspid aortic valve and concomitant single coronary ostium, which we treated by valve repair and coronary transfer.

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Liposarcomas (LPSs) are rare malignant tumors of adipocytic origin, primarily occurring in the extremities and retroperitoneum, with thoracic involvement being exceptionally rare. This case report details the surgical management and outcomes of a recurrent intrathoracic LPS in a 65-year-old male with a history of previous mediastinal tumor resection. CT imaging revealed a recurrent tumor extending into the left pleura.

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Background: Right ventricular (RV) conduit availability and degeneration are potential limitations of the Ross procedure. Pulmonary homografts are the gold standard, but their limited availability drives the need for alternatives. The aim of this study was to compare results of different RV conduits.

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Article Synopsis
  • The text discusses a severe infection caused by a bacteria usually found in the mouths of cats and dogs, which can lead to sepsis, particularly in immunocompromised patients, with a high mortality rate of 10% to 30%.
  • An 81-year-old woman developed sepsis after a dog bite and presented with serious symptoms, including thrombopenia and schistocytes, leading to her admission to the intensive care unit.
  • Despite her recovery through plasmapheresis, antibiotics, and dialysis, she required amputation of her affected fingertip and was diagnosed with a rare case of mitral valve endocarditis, which was effectively treated with antibiotics.
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Background: Aortic root remodeling is one of the principal forms of valve-preserving root replacement. Its value has been questioned by some, whereas others have achieved excellent valve durability. The purpose of this review is to summarize the existing information to determine which factors may have contributed both to failures and to successes.

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Objectives: The objective of the study was to quantify the differences in cusp size and shape in patients with normal and dilated trileaflet aortic roots and in dilated roots with or without aortic regurgitation.

Methods: A retrospective analysis of computed tomography studies in patients with normal and dilated trileaflet aortic roots was performed measuring root and cusp dimensions. Normal root size was defined as sinuses of Valsalva diameter less than 40 mm, dilated as 45 mm or greater.

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Background: Bicuspid aortic valves (BAV) are frequently associated with ascending aortic aneurysms. The etiology is incompletely understood, but genetic factors, in addition to flow perturbations, are likely involved. Since loss of contractility and elaboration of extracellular matrix in the vessel wall are features of BAV-associated aortopathy, phenotypic modulation of smooth muscle cells (SMCs) may play a role.

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Background: This study was performed to determine cusp causes of aortic regurgitation in patients with tricuspid aortic valves without significant aortic dilatation and define cusp pathologies amenable to surgical repair (aortic valve repair [AVr]) versus aortic valve replacement.

Methods And Results: We retrospectively reviewed surgical reports of consecutive adults with tricuspid aortic valves undergoing surgery for clinically significant aortic regurgitation within a prospective registry from January 2005 to September 2019. Valvular mechanisms were determined by systematic in vivo intraoperative quantification methods.

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Article Synopsis
  • - This study reviews long-term outcomes of bicuspid aortic valve (BAV) repair, focusing on the effects of commissural orientation (CO) on health results over 15 years.
  • - The research included 594 male patients, revealing high survival rates (94.8%) and significant freedom from reoperation (86.8%) and severe aortic insufficiency (70.8%) at the 15-year mark.
  • - It concluded that effective height measurement and modified CO techniques like sinus plication promote durability, while specific factors like calcification and very asymmetric CO increase reoperation risks, suggesting a need for replacement in such cases.
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Objectives: In patients with aortic root aneurysm, the aortic basal ring is frequently dilated. It has been speculated that the muscular part of the basal ring dilates most. The purpose of this study was to analyse the segmental dilatation of the basal ring, comparing normal and dilated roots in patients with tricuspid aortic valves.

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  • The study investigates optimal sizes of the annular and sinotubular junctions in aortic valve repair while keeping the cusp height constant through computer simulations.
  • A computational model created 125 virtual anatomies, finding that changes to the annular diameter had a more significant effect on valve performance than alterations in the sinotubular junction diameter.
  • Results indicate that an ideal valve configuration occurs when the sinotubular junction is 2-4 mm larger than the annulus, which leads to better coaptation height and lower stress on the valve cusps.
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Article Synopsis
  • - This document serves as an evidence-based guideline for naming and classifying congenital bicuspid aortic valve and its associated conditions, aimed at a wide range of medical professionals.
  • - It is designed for use by pediatricians, cardiologists, surgeons, and researchers, ensuring clarity across various healthcare fields.
  • - The consensus is subject to updates as new research and key findings emerge, highlighting its dynamic nature in adapting to evolving medical knowledge.
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Chronic thromboembolic pulmonary disease (CTEPD) is an important late complication of acute pulmonary embolism, in which the thrombi transform into fibrous tissue, become integrated into the vessel wall, and lead to chronic obstructions. CTEPD is differentiated into cases without pulmonary hypertension (PH), characterized by a mean pulmonary arterial pressure up to 20 mmHg and a form with PH. Then, it is still referred to as chronic thromboembolic pulmonary hypertension (CTEPH).

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Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare disease, but an important late sequela after acute pulmonary embolism. Therefore, follow-up after at least three months of sufficient anticoagulation is recommended. Patients with suspected CTEPH should be referred to specialized CTEPH centers for further evaluation and treatment.

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, an integral component of the skin's customary bacterial flora, represents a Gram-positive anaerobic bacterium characterized by its low virulence. Despite its low virulence, the pathogen can cause profound-seated infections as well as infections linked to medical devices. We report a case study of a prosthesis endocarditis accompanied by a paraaortic abscess caused by , a development occurring five years prior to composite aortic root and valve replacement.

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Article Synopsis
  • The study aimed to assess if a daily goal checklist affects the length of stay (LOS) in the pediatric cardiac intensive care unit (PCICU) after heart surgery.
  • The STANDARD group had a median LOS of 96 hours, while the control group had 101.5 hours, showing no statistically significant difference.
  • Key factors influencing prolonged LOS included age, severity of congenital heart disease (CHD), and certain clinical scores, indicating that structured goal management benefits recovery post-surgery.
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Pressure recovery (PR) is essential part of the post stenotic fluid mechanics and depends on the ratio of EOA/A, the effective aortic valve orifice area (EOA) and aortic cross-sectional area (A). In patients with advanced ascending aortic aneurysm and mildly diseased aortic valves, the effect of A on pressure recovery and corresponding functional aortic valve opening area (ELCO) was evaluated before and after valve-sparing surgery (Dacron graft implantation). 66 Patients with ascending aortic aneurysm (mean aortic diameter 57 +/- 10 mm) and aortic valve-sparing surgery (32 reimplantation technique (David), 34 remodeling technique (Yacoub)) were routinely investigated by Doppler echocardiography.

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Background: Valve-sparing root replacement (VSRR) has been associated with good survival and low rates of valve-related complications (VRCs). Whether these advantages are present irrespective of patient comorbidity or age is unclear. The aim of this study was to analyze survival and frequency of VRCs in relation to patient comorbidity and age.

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Aortic root remodeling was originally designed in the late 1980s to treat patients with tricuspid aortic valves (TAVs), aortic regurgitation (AR), and root aneurysm to normalize root dimensions. The late results showed a relevant proportion of patients who required reoperation for recurrent AR. Later observations revealed that cusp prolapse is frequently present after correction of root dilatation.

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