Publications by authors named "Hans-Joachim Janssen"
Introduction: Despite growing awareness of post-coronavirus disease 2019 (COVID-19) cholangiopathy as one of the most serious long-term gastrointestinal consequences of COVID-19, the endoscopic features of this disease are still poorly characterized. This study aimed to more precisely define its endoscopic features and to outline the role of endoscopic retrograde cholangiopancreatography (ERCP) in the management of this entity.
Methods: In this observational study, 46 patients with confirmed post-COVID-19 cholangiopathy were included.
Article Synopsis
- Increasing evidence links secondary sclerosing cholangitis (SSC) as a potential long-term complication of severe COVID-19, particularly in patients requiring invasive ventilation.
- An observational study at University Hospital Charité Berlin analyzed 1,082 ventilated COVID-19 patients, identifying that 1 in 43 developed SSC, with risk factors including systemic low oxygen levels and multi-organ failure.
- The study highlights that SSC occurs in critically ill patients, likely due to severe tissue hypoxia and related circulatory issues, predicting a rise in SSC cases in the post-COVID-19 landscape.