Publications by authors named "Hans-Christian Stein"
This study aimed to assess the concordance of various psychometric scales in detecting Perinatal Depression (PND) risk and diagnosis. A cohort of 432 women was assessed at 10-15th and 23-25th gestational weeks, 33-40 days and 180-195 days after delivery using the Edinburgh Postnatal Depression Scale (EPDS), Visual Analogue Scale (VAS), Hamilton Depression Rating Scale (HDRS), Montgomery-Åsberg Depression Rating Scale (MADRS), and Mini International Neuropsychiatric Interview (MINI). Spearman's rank correlation coefficient was used to assess agreement across instruments, and multivariable classification models were developed to predict the values of a binary scale using the other scales.
View Article and Find Full Text PDFArticle Synopsis
- The Life-ON study aimed to assess sleep quality and disorders among pregnant women and postpartum over time, involving 439 participants from local gynecological departments.
- Results showed that sleep quality worsened throughout pregnancy, with 34% experiencing poor sleep in the first trimester, rising to 71% in the first month postpartum; insomnia and excessive daytime sleepiness trends were also noted.
- The study highlights the high prevalence of sleep disorders during pregnancy and postpartum, stressing the need for routine assessments to enhance early detection and management.
Article Synopsis
- The COVID-19 pandemic led to an increase in the use of telepsychiatry, prompting a study to assess the opinions and preferences of service users, carers, and clinicians about its effectiveness.
- The study involved surveys and focus groups across four sites in the UK and Italy, revealing that telepsychiatry is convenient for specific follow-ups but lacks effectiveness in building therapeutic relationships and assessing acute mental states.
- Results indicated differing perceptions between clinicians and service users/carers about the quality of telepsychiatry during the pandemic, highlighting the need for a tailored hybrid care model that includes stakeholder preferences and further training for clinicians on telepsychiatry.
Background: Although aggressive dream content is considered a distinctive feature of REM Sleep Behavior Disorder (RBD) and patients often report violent dreams during medical interviews, nonviolent behaviors (eating, drinking, urinating) and pleasant actions (e.g laughing, singing, dancing) or simply elemental, jerky limb movements are frequently observed during video-polysomnography. As a first-line pharmacological treatment, clonazepam has been shown to reduce motor symptoms during REM sleep, but its effect on dream content remains unclear.
View Article and Find Full Text PDFBackground: Tiapride is an atypical antipsychotic used to treat alcohol withdrawal, aggressiveness and agitation, headache, dyskinesias, tic and Tourette's disorder. More recently, it has been proposed for the treatment of delirium and agitation in hospitalised patients with COVID-19. Although its safety profile makes it suitable for use in vulnerable populations, the use of tiapride for psychiatric disorders is limited.
View Article and Find Full Text PDFBackground: Depressive symptoms occur in several psychiatric disorders, often in the absence of a formal diagnosis of depression. We aimed to evaluate the efficacy and the tolerability of amisulpride, both alone and as augmentation therapy, in the treatment of depressive symptoms in individuals with any major psychiatric disorder.
Methods: We searched PubMed, Embase, PsycINFO, GreyLit, OpenGrey and ProQuest up to March 2020 for randomised controlled trials focussing on the treatment of an acute depressive episode in any major psychiatric disorder.