Publications by authors named "Hans v d Linden"
Article Synopsis
- Endobronchial carcinoma evolves through identifiable pre-cancerous changes, but no reliable marker exists to predict their behavior.
- A study analyzed endobronchial lesions from patients without visible lung cancer, finding that abnormal p53 protein expression (suprabasal p53) was more frequent in severely dysplastic lesions.
- Among patients followed up, those with suprabasal p53 staining in biopsies were more likely to develop bronchial carcinoma, indicating that this marker may help predict cancer risk in pre-neoplastic lesions.
