Publications by authors named "Hans den Boer"

Article Synopsis
  • A significant rise in multidrug-resistant microorganisms (MDRO) was noted following the transfer of Ukrainian patients to hospitals, with various resistant strains identified, including carbapenem-resistant bacteria.
  • Testing for antimicrobial susceptibility showed low efficacy rates for several last-resort antibiotics, highlighting severe resistance issues among these pathogens.
  • Factors influencing cefiderocol susceptibility results include testing methods and standards used, making understanding resistance patterns crucial for treating patients suspected of Gram-negative infections with recent hospitalizations in Ukraine.
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The enhancement of central serotonin system function underlies the therapeutic effects of selective serotonin reuptake inhibitors (SSRIs), which have become the most commonly used class of antidepressant agents. However, many individuals experience depressive episodes that are resistant to SSRI treatment. Homeostatic mechanisms that limit the extent to which SSRIs enhance serotonergic neurotransmission have been implicated in this phenomenon.

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