Shared Decision-Making Training in Internal Medicine: A Multisite Intervention Study.

Background: Research shows that when patients and health care providers share responsibility for clinical decisions, both patient satisfaction and quality of care increase, and resource use decreases. Yet few studies have assessed how to train residents to use shared decision-making (SDM) in their practice.

Objective: We developed and evaluated a SDM training program in internal medicine.

The novel TLR-9 agonist QbG10 shows clinical efficacy in persistent allergic asthma.

Background: Allergen-specific TH2 responses contribute to the development of allergic asthma. Their increase may be due to a reduced early exposure to environmental pathogens, which induces a TH1 response, and thereby suppresses the allergic TH2 response. QbG10 (bacteriophage Qbeta-derived virus-like particle with CpG-motif G10 inside), a novel Toll-like receptor 9 agonist packaged into virus-like particles, was designed to stimulate the immune system toward a TH1-mediated protective response.

Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study.

Background: Hypertension can be controlled adequately with existing drugs such as angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers. Nevertheless, treatment success is often restricted by patients not adhering to treatment. Immunisation against angiotensin II could solve this problem.

Floppy kid syndrome caused by D-lactic acidosis in goat kids.

Background: Goat kids with floppy kid syndrome have metabolic acidosis, muscle weakness, and depression but no dehydration.

Hypothesis: D-Lactate is the major component of acidemia in goat kids with floppy kid syndrome.

Animals: Fifty-five goat kids with floppy kid syndrome (group F) and 35 clinically healthy goat kids (group C).