Publications by authors named "Hans P Raue"
Age-related changes in the immune system increase susceptibility to infectious diseases. Vaccines are an important tool to prevent infection or boost immunological memory; however, vaccines are less effective in aged individuals. In order to protect our aging population from the threat of infectious diseases, we must gain a better understanding of age-related alterations in the immune response at the site of infection.
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- CLL patients often face severe immune dysfunction, making standard COVID-19 vaccines less effective, prompting the exploration of a heterologous boost for those who didn't respond to the initial vaccine series.
- Two CLL patients were observed in a study after receiving a third dose of a different COVID-19 vaccine (Ad26.COV2.S) to assess their immune response.
- Following this third dose, one patient showed a positive immune response with significant antibody and T-cell production, while the other did not demonstrate similar improvements.