Publications by authors named "Hans Martin Dahl Aguilera"
Characterisation of global and regional mitral annular strains in an acute porcine model.
Interdiscip Cardiovasc Thorac Surg
September 2024
Article Synopsis
- The study focused on assessing mitral annular strain using a new computational technique in pigs.
- Results indicated that global annular strain decreases after isovolumetric contraction, with the P2 segment showing the greatest shortening while the anterior segment deformed the least.
- The findings suggest that mitral annular strain has significant regional differences and remains stable despite changes in preload and afterload, correlating instead with left ventricular contractility.
The purpose of this study was to investigate the effects of loading conditions and left ventricular (LV) contractility on mitral annular dynamics. In 10 anesthetized pigs, eight piezoelectric transducers were implanted equidistantly around the mitral annulus. High-fidelity catheters measured left ventricular pressures and the slope of the end-systolic pressure-volume relationship (E ) determined LV contractility.
View Article and Find Full Text PDFObjectives: Barlow's mitral valve disease with late systolic mitral regurgitation provides diagnostic and therapeutic challenges. The mechanisms of the regurgitation are still unclear. We hypothesized that the onset and the severity of late systolic regurgitation are determined by annulus dynamics and the mechanical stresses imposed by the left ventricle.
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