Publications by authors named "Hans Langenhuijsen"
Background: The use of low intra-abdominal pressure (<10 mmHg) reduces postoperative pain scores after laparoscopic surgery.
Objective: To investigate whether low-pressure pneumoperitoneum with deep neuromuscular blockade improves the quality of recovery after laparoscopic donor nephrectomy (LDN).
Design, Setting And Participants: In a single-center randomized controlled trial, 64 live kidney donors were randomly assigned to 6 or 12 mmHg insufflation pressure.
Article Synopsis
- The study explores the use of a dual-labeled antibody (girentuximab) for targeted imaging of clear cell renal cell carcinoma (ccRCC) during surgery, combining near-infrared fluorescence and radionuclide imaging.
- Seven kidney specimens from ccRCC patients were perfused with the dual-labeled antibody, and imaging techniques were used to visualize its accumulation in tumor tissue compared to normal tissue.
- Results showed significant accumulation of the antibody in ccRCC tissue, supporting the potential for dual-modality imaging as a reliable tool for detecting this cancer during surgical procedures.