Publications by authors named "Hans L Busch"

Article Synopsis
  • β-Endorphin plays a key role in mood, pain management, immune function, and behavior stability, and is produced in the nervous system and skin, especially in response to UV light.
  • A study investigated the effects of visible blue light on β-endorphin production in human skin cells and found that blue light exposure significantly increased β-endorphin levels both in skin cell cultures and in healthy individuals.
  • The study suggested that the increase in β-endorphin is linked to the non-enzymatic production of nitric oxide, which enhances β-endorphin production in both skin cells and possibly in the brain, highlighting a multi-step process facilitated by nitric oxide.
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Statins are recommended as first-line therapy for patients with hypercholesterolaemia. A sizable proportion of patients, however, does not reach therapeutic goals, is statin intolerant, or, despite optimal statin therapy, is at high risk of ischaemic events. Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a major role in lipid metabolism and several comorbidities.

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